N,N-Diethyl-2,2,2-trifluoroacetamide
N,N-Diethyl-2,2,2-trifluoroacetamide (CAS: 360-92-9) is a fluorinated amide with the molecular formula C6H12F3NO and a molecular weight of 169.14 g/mol. Supplied by Tech Serve Solutions with an assay of 99%, this compound serves as a valuable building block in organic synthesis. Its properties make it suitable for chemical research and development, particularly in reactions requiring a trifluoroacetylating agent or as an intermediate in the synthesis of more complex molecules.
- Synonyms
- 2-trifluoroacetamideCF3CON(C2H5)2

Organic Synthesis Intermediate
N,N-Diethyl-2,2,2-trifluoroacetamide is utilised as a key intermediate in the construction of various organic molecules. Its trifluoroacetyl group can be selectively introduced into other compounds, facilitating the synthesis of fluorinated pharmaceuticals and agrochemicals.
Trifluoroacetylation Reagent
This compound can function as a trifluoroacetylating agent in organic chemistry. It is employed to introduce the trifluoroacetyl group (CF3CO-) onto alcohols, amines, and other nucleophiles, modifying their properties or preparing them for further transformations.
Building Block for Fluorochemicals
As an organic building block containing fluorine, it is instrumental in the development of novel fluorinated materials and speciality chemicals. Its specific structure lends itself to applications where fluorine incorporation is desired for enhanced stability or unique reactivity.
| Molecular weight | 169.14 |
|---|---|
| Linear formula | CF3CON(C2H5)2 |
| Assay | 99% |
| Boiling point | 65-67 °C/24 mmHg(lit.) |
| Density | 1.2 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.38(lit.) |


Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 43 °C / 109.4 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 10-20/21/22-36/37/38 |
| Safety statements (S) | 16-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N,N-Diethyl-2,2,2-trifluoroacetamide used for?
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N,N-Diethyl-2,2,2-trifluoroacetamide is primarily used as an intermediate in organic synthesis and as a trifluoroacetylating agent for introducing the trifluoroacetyl group into other molecules, particularly in the development of fluorinated compounds.
What is the CAS number and formula for N,N-Diethyl-2,2,2-trifluoroacetamide?
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The CAS number for N,N-Diethyl-2,2,2-trifluoroacetamide is 360-92-9 and its linear formula is CF3CON(C2H5)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N,N-Diethyl-2,2,2-trifluoroacetamide with a purity of 99%. TSS does not represent this product as USP, BP, or EP grade.
How should N,N-Diethyl-2,2,2-trifluoroacetamide be handled?
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N,N-Diethyl-2,2,2-trifluoroacetamide is a flammable liquid and vapour (H226), and is harmful if swallowed (H302), in contact with skin (H312), or if inhaled (H332). It also causes skin irritation (H315) and serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including safety glasses, face shields, gloves, and respiratory protection, must be used. Handle in a well-ventilated area.
How is N,N-Diethyl-2,2,2-trifluoroacetamide packed and shipped?
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N,N-Diethyl-2,2,2-trifluoroacetamide is packed and shipped according to international regulations for hazardous materials, including UN 1993, Class 3, Packing Group III. TSS exports globally.
How can I request a sample or quote for N,N-Diethyl-2,2,2-trifluoroacetamide?
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To request a sample or a quote for N,N-Diethyl-2,2,2-trifluoroacetamide, please contact the TSS sales department through our website or by phone.
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