N-Cyclohexylhydroxylamine
N-Cyclohexylhydroxylamine (CAS: 2211-64-5; Formula: C <sub>6</sub> H <sub>11</sub> NHOH) is a valuable organic compound with a molecular weight of 115.17 g/mol. It functions primarily as a reactant in various chemical syntheses. Its applications include catalysing intermolecular hydroamination reactions, participating in condensation reactions, and serving as a precursor in the development of potential antitumor agents and bradykinin B1 receptor antagonists.
- IUPAC
- N-Hydroxycyclohexanamine,N-Hydroxycyclohexylamine
- Synonyms
- N-HydroxycyclohexanamineN-Hydroxycyclohexylamine
Intermolecular Hydroamination
N-Cyclohexylhydroxylamine acts as a reactant in aldehyde-catalyzed intermolecular hydroamination reactions, contributing to the synthesis of complex organic molecules.
Condensation Reactions
This compound is utilised in various condensation reactions, forming new chemical bonds and structures essential for further synthesis.
Antitumor Agent Precursor
It serves as a key intermediate in the preparation of cyclin-dependent kinase inhibitors, explored for their potential as antitumor agents.
Bradykinin Receptor Antagonist Synthesis
N-Cyclohexylhydroxylamine is employed in the preparation of hydroxyurea derivatives investigated as small molecule bradykinin B1 receptor antagonists.
| Molecular weight | 115.17 |
|---|---|
| Linear formula | C6H11NHOH |
| Storage temperature | −20°C |
| Application | Reactant for:• Aldehyde-catalyzed intermolecular hydroamination1• Condensation reactions2• Preparation of cyclin-dependent kinase inhibitors selective for multiple cyclin-dependent kinases for potential use as antitumor agents3• Preparation of hydroxyurea derivatives as small molecule bradykinin B1 receptor antagonists4 |
| Melting point | 139-140 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Cyclohexylhydroxylamine used for?
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N-Cyclohexylhydroxylamine is primarily used as a reactant in chemical syntheses, including aldehyde-catalyzed intermolecular hydroamination, condensation reactions, and the preparation of potential antitumor agents and bradykinin B1 receptor antagonists.
What is the CAS number and formula for N-Cyclohexylhydroxylamine?
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The CAS number for N-Cyclohexylhydroxylamine is 2211-64-5, and its linear formula is C <sub>6</sub> H <sub>11</sub> NHOH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Cyclohexylhydroxylamine typically as a research or technical grade material. We do not represent it as meeting USP, BP, or EP pharmacopoeia standards unless explicitly stated in the product documentation.
How should N-Cyclohexylhydroxylamine be handled safely?
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N-Cyclohexylhydroxylamine is classified as Dangerous (GHS05, GHS07) with the signal word Danger. It is harmful if swallowed (H302) and causes serious eye damage (H318). Appropriate personal protective equipment, including eyeshields, gloves, and a dust mask (N95), should be used. Handle in a well-ventilated area.
Is N-Cyclohexylhydroxylamine supplied globally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including N-Cyclohexylhydroxylamine.
How can I request a quote or sample?
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Please contact our sales team via the website or directly to request a quote or sample of N-Cyclohexylhydroxylamine.
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