N-Boc-3-aminothiophene-2-carboxaldehyde
N-Boc-3-aminothiophene-2-carboxaldehyde (CAS: 368442-47-1), a vital heterocyclic building block with the molecular formula C10H13NO3S and a molecular weight of 227.28 g/mol, serves as a key intermediate in organic synthesis. It is particularly useful for introducing substituted thiophene moieties into more complex molecular structures. This compound is primarily utilised in research and development settings for the creation of novel chemical entities.
- IUPAC
- 3-(N-Boc-amino)-2-thiophenecarbaldehyde,3-(N-Boc-amino)-2-thiophenecarboxaldehyde,3-(Boc-amino)thiophene-2-carboxaldehyde,N-Boc-3-amino-2-formylthiophene
- Synonyms
- 3-(N-Boc-amino)-2-thiophenecarbaldehyde3-(N-Boc-amino)-2-thiophenecarboxaldehyde3-(Boc-amino)thiophene-2-carboxaldehydeN-Boc-3-amino-2-formylthiophene

Organic Synthesis Intermediate
This compound functions as a versatile intermediate in the synthesis of complex organic molecules, particularly those incorporating thiophene rings. Its aldehyde and protected amine functionalities allow for diverse chemical transformations.
Pharmaceutical Research
It is employed in the early stages of drug discovery and development as a building block for creating potential therapeutic agents. The thiophene core is present in numerous biologically active compounds.
Materials Science
The unique structural features of thiophene derivatives can be leveraged in the design of novel materials with specific electronic or optical properties.
| Molecular weight | 227.28 |
|---|---|
| Empirical formula | C10H13NO3S |
| Assay | 97% |
| Density | 1.186 g/mL at 25 °C |
| Refractive index | n20/D 1.561 |

Hazard statements
- H302Harmful if swallowed
- H317May cause an allergic skin reaction
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Flash point | >110 °C / >230 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-43 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Boc-3-aminothiophene-2-carboxaldehyde used for?
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N-Boc-3-aminothiophene-2-carboxaldehyde is used as a versatile building block in organic synthesis, particularly in the research and development of novel chemical entities, including potential pharmaceutical agents and materials.
What are the CAS number and chemical formula for this compound?
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The CAS number is 368442-47-1, and the chemical formula is C10H13NO3S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Boc-3-aminothiophene-2-carboxaldehyde with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should N-Boc-3-aminothiophene-2-carboxaldehyde be handled?
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This compound is classified as harmful if swallowed and may cause an allergic skin reaction (H302, H317). Handle with appropriate personal protective equipment, including gloves and protective clothing (P280), and avoid contact with skin. Ensure adequate ventilation.
Is this chemical regulated or controlled?
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The provided data does not indicate that N-Boc-3-aminothiophene-2-carboxaldehyde is a controlled or scheduled substance.
How is this chemical packed and exported?
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Tech Serve Solutions packs and exports chemicals adhering to all relevant safety and transport regulations to ensure secure delivery worldwide.
How can I request a sample or quote?
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To request a sample or a quotation for N-Boc-3-aminothiophene-2-carboxaldehyde, please contact our sales team through the website or by phone.
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