N-Boc-3-aminothiophene
N-Boc-3-aminothiophene (CAS: 19228-91-2) is a valuable heterocyclic building block with the molecular formula C9H13NO2S and a molecular weight of 199.27 g/mol. This thiophene derivative, featuring a Boc-protected amine group, is essential for introducing specific functionalities in organic synthesis. It serves as a key intermediate in the research and development of novel compounds within the pharmaceutical and fine chemical industries.
- IUPAC
- 3-(tert-Butoxycarbonylamino)thiophene,3-Thiophenecarbamic acid tert-butyl ester,N-3-Thienylcarbamic acid 1,1-dimethylethyl ester
- Synonyms
- 3-(tert-Butoxycarbonylamino)thiophene3-Thiophenecarbamic acid tert-butyl esterN-3-Thienylcarbamic acid 1,1-dimethylethyl ester

Organic Synthesis Intermediate
N-Boc-3-aminothiophene is widely employed as a versatile building block in complex organic synthesis. Its structure allows for regioselective functionalization, enabling the construction of more intricate molecular architectures.
Pharmaceutical Research
This compound is a crucial intermediate in the development of new pharmaceutical agents. Its thiophene core and protected amine group are frequently incorporated into drug candidates targeting various therapeutic areas.
Materials Science
The unique electronic properties of thiophene derivatives make N-Boc-3-aminothiophene a potential component in the synthesis of functional materials, such as organic semiconductors or conductive polymers.
| Molecular weight | 199.27 |
|---|---|
| Empirical formula | C9H13NO2S |
| Assay | 96% |
| Storage temperature | 2-8°C |
| Melting point | 135-140 °C |

Hazard statements
- H302Harmful if swallowed
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Boc-3-aminothiophene primarily used for?
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N-Boc-3-aminothiophene is primarily used as a versatile building block in organic synthesis, particularly in pharmaceutical research and the development of fine chemicals. Its protected amine and thiophene core are valuable for constructing complex molecules.
What are the CAS number and molecular formula for N-Boc-3-aminothiophene?
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The CAS number for N-Boc-3-aminothiophene is 19228-91-2, and its molecular formula is C9H13NO2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Boc-3-aminothiophene with an assay of 96%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
How should N-Boc-3-aminothiophene be handled safely?
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N-Boc-3-aminothiophene is classified as harmful if swallowed (H302) and requires careful handling. It is a Warning substance. Store at 2-8°C. Always consult the Safety Data Sheet (SDS) before use and wear appropriate personal protective equipment.
Is N-Boc-3-aminothiophene available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including N-Boc-3-aminothiophene. We can ship this product to research institutions and companies worldwide.
How can I request a quote or sample for N-Boc-3-aminothiophene?
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To request a quote or a sample of N-Boc-3-aminothiophene, please contact our sales department via the website or provide your details through the 'Request Information' form.
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