N-(6-Amino-pyridin-2-yl)-2,2-dimethyl-propionamide
N-(6-Amino-pyridin-2-yl)-2,2-dimethyl-propionamide (CAS 132784-74-8; C10H15N3O; molar mass 193.25 g/mol) is a heterocyclic building block belonging to the aminopyridine pivalamide family. It pairs a 2,6-disubstituted pyridine core bearing a free amino group with a pivaloyl (2,2-dimethylpropionyl) amide, giving a stable, directing handle widely used in chemical synthesis. Tech Serve Solutions supplies it as a research-grade intermediate for pharmaceutical and fine-chemical discovery programmes worldwide.
- Synonyms
- N-(6-Amino-pyridin-2-yl)-2,2-dimethyl-propionamideN-(6-Aminopyridin-2-yl)-2,2-dimethylpropanamideN-(6-Aminopyridin-2-yl)pivalamide2,2-Dimethyl-N-(6-aminopyridin-2-yl)propanamideN-(6-Amino-2-pyridyl)pivalamideCAS 132784-74-8
Heterocyclic building block
Serves as a functionalised pyridine scaffold in multi-step synthesis. The combination of a free amino group and a pivalamide on adjacent ring positions provides distinct, selectively addressable reactive sites for further elaboration.
Pharmaceutical intermediate
Used in medicinal-chemistry and drug-discovery programmes where substituted 2-aminopyridines are common motifs. It is offered for research and development use, not as a finished active pharmaceutical ingredient.
Amino-directed functionalisation
The pivaloyl amide is a well-established protecting and directing group in pyridine chemistry, supporting regioselective metalation and cross-coupling. This makes the compound a convenient handle for building more complex nitrogen heterocycles.
Reference and laboratory reagent
Suitable as a characterised reagent for method development, analytical reference work and exploratory synthesis in research laboratories.
| Molecular weight | 193.25 |
|---|---|
| Empirical formula | C10H15N3O |
Hazard statements
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(6-Amino-pyridin-2-yl)-2,2-dimethyl-propionamide used for?
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It is used mainly as a heterocyclic building block and pharmaceutical intermediate in chemical synthesis. The molecule combines a 2-aminopyridine core with a pivaloyl amide, making it a useful, selectively reactive scaffold for assembling more complex nitrogen heterocycles in research and development.
What is the CAS number and molecular formula of N-(6-Amino-pyridin-2-yl)-2,2-dimethyl-propionamide?
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The CAS number is 132784-74-8. The empirical formula is C10H15N3O (Hill notation) with a molecular weight of 193.25 g/mol.
What grade and purity does Tech Serve Solutions supply?
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We supply this compound as a research-grade synthesis intermediate. The supplied data does not specify a fixed assay, so purity is confirmed per batch on the certificate of analysis. We do not represent it as USP, BP or EP pharmacopoeial grade; please share your specification and we will confirm availability against it.
What are the safety and handling requirements?
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It is classified under GHS07 with the signal word Warning and hazard statement H319 (causes serious eye irritation). Wear suitable eye protection and gloves, avoid generating dust, and follow the precaution P305+P351+P338: IF IN EYES, rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, and continue rinsing. It carries a German Water Hazard Class (WGK) of 3. Always consult the current Safety Data Sheet before use.
How is N-(6-Amino-pyridin-2-yl)-2,2-dimethyl-propionamide packed, shipped and exported?
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It is packed in tightly closed, appropriately labelled containers sized from gram research quantities to larger project volumes, with packaging selected to suit the order. Tech Serve Solutions handles documentation and export logistics to support global delivery, and each consignment ships with its Safety Data Sheet and certificate of analysis.
How do I request a sample or quote?
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Contact Tech Serve Solutions with the product name, CAS number 132784-74-8, your required quantity and any target specification. We will respond with availability, lead time and a quotation, and can arrange a sample where appropriate.
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