Morpholine, polymer-bound
Morpholine, polymer-bound (CAS: 138048-80-3) is a solid-supported tertiary amine featuring a molecular weight of 411.58 g/mol. This versatile reagent functions effectively as a base and acid scavenger in various organic syntheses. It is particularly useful in the preparation of sulfonamides and amides, and as a catalyst for the functionalisation of secondary amines with acid chlorides. Its polymer-bound nature facilitates easy separation from reaction mixtures.
- Synonyms
- Morpholine, polymer-bound

Sulfonamide and Amide Synthesis
This polymer-bound morpholine derivative serves as an effective base in the synthesis of sulfonamides and amides. Its solid support allows for straightforward removal after the reaction, simplifying product purification.
Catalyst for Amine Functionalisation
It acts as a catalyst in the functionalisation of secondary amines with acid chlorides. The polymer-bound nature ensures easy separation of the catalyst post-reaction.
Acid Scavenger in Organic Synthesis
The resin functions as a polymer-bound base, efficiently scavenging excess acid generated during various synthetic transformations, thereby improving reaction control and yield.
| Molecular weight | 411.58 |
|---|---|
| Empirical formula | C29H33NO |
| Particle size | 200-400 mesh |
| Application | This polymer-bound tertiary amine is used as a base in the synthesis of sulfonamides and amides, serves as a catalyst in the functionalization of secondary amines, with acid chlorides. The resin was also used as a polymer-bound base to scavenge excess acid. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Crosslinking | 1 % cross-linked |
|---|---|
| Extent Of Labeling | 2.75-3.25 mmol/g loading |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Morpholine, polymer-bound used for?
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Morpholine, polymer-bound is used as a base in the synthesis of sulfonamides and amides, as a catalyst for the functionalisation of secondary amines with acid chlorides, and as an acid scavenger in organic synthesis. Its polymer support facilitates easy separation.
What is the CAS number and formula for Morpholine, polymer-bound?
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The CAS number for Morpholine, polymer-bound is 138048-80-3. The empirical formula (Hill notation) is C29H33NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Morpholine, polymer-bound with a loading of 2.75-3.25 mmol/g. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, or EP grade.
What are the safety and handling precautions for Morpholine, polymer-bound?
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When handling Morpholine, polymer-bound, it is essential to wear eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The product has a WGK rating of 3 in Germany, indicating a high hazard to water.
How is Morpholine, polymer-bound packed, shipped, and exported?
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Morpholine, polymer-bound is carefully packed to maintain its integrity during transit. Tech Serve Solutions has extensive experience in global shipping and exporting fine chemicals and reagents.
How can I request a sample or quote for Morpholine, polymer-bound?
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To request a sample or a quotation for Morpholine, polymer-bound, please contact the Tech Serve Solutions sales team through our website or by phone.
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