(+)-MK-801 hydrogen maleate
(+)-MK-801 hydrogen maleate (CAS: 77086-22-7), a potent NMDA receptor antagonist, is supplied by Tech Serve Solutions as a white powder. With a molecular weight of 337.37 g/mol and empirical formula C16H15N · C4H4O4, this compound is a valuable research tool in neuroscience. Its primary applications lie in the study of excitatory amino acid neurotransmission and ionotropic glutamate receptor modulation, contributing to a deeper understanding of neurological processes.
- IUPAC
- (5S,10R)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine hydrogen maleate,Dizocilpine hydrogen maleate
- Synonyms
- Dizocilpine hydrogen maleate
Neuroscience Research
(+)-MK-801 hydrogen maleate is extensively used as a pharmacological tool to investigate the role of NMDA receptors in various neurological functions and disorders. It aids in studying excitotoxicity and neuroprotection mechanisms.
Cell Signaling Studies
This compound serves as a modulator of ionotropic glutamate receptors, facilitating research into cell signaling pathways within the central nervous system. It helps elucidate the complex interactions of neurotransmitters.
Ion Channel Modulation Research
As a ligand-gated ion channel modulator, (+)-MK-801 hydrogen maleate is employed to study the gating mechanisms and functional properties of specific ion channels crucial for neuronal activity.
| Molecular weight | 337.37 |
|---|---|
| Empirical formula | C16H15N · C4H4O4 |
| Form | powder |
| Colour | white |
| Solubility | DMSO: >20 mg/mLH2O: soluble6 mg/mL0.1 M HCl: solubleethanol: soluble |
| Optical activity | [α]25/D +117°, c = 1 in methanol(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (+)-MK-801 hydrogen maleate used for?
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(+)-MK-801 hydrogen maleate is primarily used as a research chemical to study NMDA receptor function, ionotropic glutamate receptors, and related neurological processes in neuroscience and cell biology.
What is the CAS number and formula for (+)-MK-801 hydrogen maleate?
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The CAS number is 77086-22-7, and the formula is C16H15N · C4H4O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (+)-MK-801 hydrogen maleate as a research-grade chemical. The assay and purity are detailed in the product specifications; we do not represent it as USP, BP, or EP grade.
How should (+)-MK-801 hydrogen maleate be handled?
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Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, due to its potential hazards.
Is (+)-MK-801 hydrogen maleate a controlled substance?
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Data provided does not indicate that (+)-MK-801 hydrogen maleate is a controlled substance. Please consult local regulations for specific guidance.
How is (+)-MK-801 hydrogen maleate packed and shipped?
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Tech Serve Solutions packs and ships chemicals according to industry best practices and international shipping regulations. For specific export details, please inquire.
How can I request a quote or sample for (+)-MK-801 hydrogen maleate?
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To request a quote or sample, please use the contact form on our website or contact our sales department directly with your inquiry.
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