2,3-Dichlorothiophene
2,3-Dichlorothiophene (CAS: 17249-79-5) is a halogenated heterocyclic compound with the molecular formula C4H2Cl2S and a molecular weight of 153.03 g/mol. This versatile thiophene derivative serves as a key building block in organic synthesis. It is particularly useful in the preparation of complex molecules, including the synthesis of enediyne-chlorophyll derivatives with potential antitumor activity and in selective electrochemical silylation reactions.
- Synonyms
- C4H2Cl2S2,3-Dichlorothiophen2,3-dichloro-thiophene
Antitumor Agent Precursor
Used as a reactant in the synthesis of enediyne-chlorophyll derivatives, which are explored for their potential as antitumor cytotoxic conjugates.
Electrochemical Synthesis
Functions as a reactant in selective electrochemical mono- and polysilylation processes, enabling specific chemical modifications.
Heterocyclic Chemistry
A valuable building block in heterocyclic synthesis, particularly for creating substituted thiophene structures used in advanced materials and pharmaceuticals.
| Molecular weight | 153.03 |
|---|---|
| Empirical formula | C4H2Cl2S |
| Boiling point | 173-174 °C/760 mmHg(lit.) |
| Density | 1.456 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.568(lit.) |
| Storage temperature | 2-8°C |
| Application | Reactant for:• Synthesis of enediyne-chlorophyll derivatives as antitumor cytotoxic conjugates1• Selective electrochemical mono- and polysilylation2 |
Hazard statements
- H301Toxic if swallowed
- H318Causes serious eye damage
- H334May cause allergy or asthma symptoms if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P342
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 70 °C / 158 °F |
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-43 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3-Dichlorothiophene used for?
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2,3-Dichlorothiophene is used as a reactant in the synthesis of enediyne-chlorophyll derivatives with potential antitumor activity and in selective electrochemical mono- and polysilylation reactions. It also serves as a general building block in organic and heterocyclic synthesis.
What are the CAS number and formula for 2,3-Dichlorothiophene?
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The CAS number for 2,3-Dichlorothiophene is 17249-79-5, and its empirical formula (in Hill notation) is C4H2Cl2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,3-Dichlorothiophene with a purity of 97%. This product is typically considered a research or technical grade chemical and is not represented as USP, BP, or EP grade.
How should 2,3-Dichlorothiophene be handled safely?
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2,3-Dichlorothiophene is a Danger substance (GHS05, GHS06, GHS08) that is toxic if swallowed and causes serious eye damage. Handle with extreme care using appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator. Ensure adequate ventilation.
How is 2,3-Dichlorothiophene packed and exported?
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2,3-Dichlorothiophene is packed and exported according to international shipping regulations for hazardous materials (UN 2810, Class 6.1, PG III). Specific packaging details are available upon request.
How can I request a quote or sample?
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To request a quote or a sample of 2,3-Dichlorothiophene, please contact our sales department through the website or by phone. Please provide your shipping details and the quantity required.
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