Methyl trichloroacetate
Methyl trichloroacetate (CAS: 598-99-2), with the chemical formula CCl3CO2CH3, is a notable organic ester. This compound serves as a valuable reagent in chemical synthesis, particularly within the realms of organic building blocks and carbonyl compounds. Its specific applications and reactivity make it a useful intermediate for researchers and industrial chemists. The compound has a molecular weight of 177.41 g/mol.
Protein Staining and Analysis
Methyl trichloroacetate has been utilised in negative staining techniques for proteins. This method allows for the subsequent recovery of unmodified proteins, facilitating further biological studies or amino acid sequencing.
Organic Synthesis Intermediate
As a functionalised ester and carbonyl compound, methyl trichloroacetate serves as a versatile building block in organic synthesis. It can be employed in reactions requiring its specific structural and electronic properties.
Reagent in Chemical Research
This compound is a useful reagent for laboratory-scale chemical research and development. Its properties lend themselves to various transformations and synthetic pathways.
| Molecular weight | 177.41 |
|---|---|
| Linear formula | CCl3CO2CH3 |
| Assay | 99% |
| Boiling point | 152-153 °C(lit.) |
| Density | 1.488 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.455(lit.) |
| Application | Methyl trichloroacetate was used for negative staining of protein that allowed unmodified proteins to be recovered for biological studies or transblot for amino acid sequence1. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 72 °C / 161.6 °F |
| Transport (UN / ADR) | UN 2533 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl trichloroacetate used for?
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Methyl trichloroacetate (CAS: 598-99-2) has been used for negative staining of proteins, enabling the recovery of unmodified proteins for further biological studies or amino acid sequencing. It also serves as a building block in organic synthesis.
What is the CAS number and formula for Methyl trichloroacetate?
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The CAS number for Methyl trichloroacetate is 598-99-2 and its linear formula is CCl3CO2CH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl trichloroacetate with a minimum purity of 99%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should Methyl trichloroacetate be handled safely?
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Methyl trichloroacetate is classified as a Warning substance, with hazards including skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment such as eyeshields, gloves, and suitable respiratory protection should be used. Handle in a well-ventilated area and avoid contact with skin, eyes, and clothing.
How is Methyl trichloroacetate packed and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter, packs and ships chemicals like Methyl trichloroacetate in compliance with international regulations to ensure safe transit worldwide.
How can I request a sample or quote for Methyl trichloroacetate?
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To request a sample or a quote for Methyl trichloroacetate, please contact the Tech Serve Solutions sales team via the website or listed contact details.
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