L-Methionine 7-amido-4-methylcoumarin trifluoroacetate salt
L-Methionine 7-amido-4-methylcoumarin trifluoroacetate salt (CAS 94367-35-8) is a fluorescent enzyme substrate with the molecular formula C15H18N2O3S · C2HF3O2 and a molecular weight of 420.40. This trifluoroacetate salt is primarily used in biochemical research to study the kinetics and specificity of aminopeptidases, particularly methionine aminopeptidase (hMetAP2). Its fluorescent properties allow for sensitive detection and quantification in enzymatic assays.
Study of Methionine Aminopeptidase
L-Methionine 7-amido-4-methylcoumarin trifluoroacetate serves as a substrate to investigate the enzymatic activity and kinetic parameters of methionine aminopeptidase (hMetAP2).
Aminopeptidase Specificity Assessment
This compound can be used alongside other substrates to determine the substrate specificity profile of various aminopeptidases through controlled enzymatic reactions.
Fluorescent Enzyme Assays
The coumarin moiety allows for sensitive, fluorescence-based detection of enzyme activity, making it valuable for high-throughput screening and biochemical investigations.
| Molecular weight | 420.40 |
|---|---|
| Empirical formula | C15H18N2O3S · C2HF3O2 |
| Assay | ≥99.0% (sum of enantiomers, HPLC) |
| Optical activity | [α]20/D +68±3°, c = 1% in methanol |
| Storage temperature | 2-8°C |
| Application | L-Methionine 7-amido-4-methylcoumarin trifluoroacetate and its analogues may be used to study the kinetics of methionine aminopeptidase (hMetAP2). L-Methionine 7-amido-4-methylcoumarin trifluoroacetate may be use with other substrates to assess the specificity of various aminopeptidases. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-Methionine 7-amido-4-methylcoumarin trifluoroacetate salt used for?
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This compound is used as a fluorescent substrate to study the kinetics and specificity of aminopeptidases, particularly methionine aminopeptidase (hMetAP2), in biochemical research.
What are the CAS number and formula for L-Methionine 7-amido-4-methylcoumarin trifluoroacetate salt?
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The CAS number is 94367-35-8, and the formula is C15H18N2O3S · C2HF3O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-Methionine 7-amido-4-methylcoumarin trifluoroacetate salt with an assay of ≥99.0% (sum of enantiomers, HPLC). TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated.
How should L-Methionine 7-amido-4-methylcoumarin trifluoroacetate salt be handled safely?
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This compound is a Warning substance that may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, in a well-ventilated area.
How is L-Methionine 7-amido-4-methylcoumarin trifluoroacetate salt typically stored and shipped?
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The product should be stored at 2-8°C. TSS exports fine chemicals and reagents globally, ensuring appropriate packaging and documentation for international shipment.
How can I request a sample or obtain a quote for this product?
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To request a sample or a quotation, please contact the TSS sales team through our website or by phone, providing the product name and CAS number.
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