(−)-Methyl (S)-3-bromo-2-methylpropionate
(−)-Methyl (S)-3-bromo-2-methylpropionate (CAS 98190-85-3) is a chiral building block with the molecular formula BrCH₂CH(CH₃)CO₂CH₃ and a molecular weight of 181.03 g/mol. This ester is primarily utilised in asymmetric synthesis and general chemical synthesis as a valuable organic building block. Its defined stereochemistry makes it useful for constructing complex chiral molecules in various research and development applications.
- IUPAC
- (−)-Methyl (S)-β-bromoisobutyrate
- Synonyms
- (−)-Methyl (S)-β-bromoisobutyrate

Chiral Building Block
Utilised in the synthesis of enantiomerically pure compounds. Its stereogenic centre allows for precise control in building complex chiral architectures.
Asymmetric Synthesis
Serves as a key intermediate in stereoselective reactions, enabling the formation of specific stereoisomers crucial for pharmaceutical and agrochemical development.
Organic Synthesis Intermediate
Functions as a versatile reagent in organic chemistry for introducing specific functional groups and structural motifs into target molecules.
| Molecular weight | 181.03 |
|---|---|
| Linear formula | BrCH2CH(CH3)CO2CH3 |
| Assay | 97% |
| Boiling point | 97.5-98.5 °C/62 mmHg(lit.) |
| Density | 1.422 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.455(lit.) |
| Optical activity | [α]20/D −23 to −16°, c = 5 neat |
| Optical purity | ee: 99% (GLC) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 73 °C / 163.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (–)-Methyl (S)-3-bromo-2-methylpropionate used for?
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(–)-Methyl (S)-3-bromo-2-methylpropionate is used in asymmetric synthesis and general chemical synthesis as a chiral building block.
What is the CAS number and chemical formula for (–)-Methyl (S)-3-bromo-2-methylpropionate?
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The CAS number is 98190-85-3 and the linear chemical formula is BrCH₂CH(CH₃)CO₂CH₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (–)-Methyl (S)-3-bromo-2-methylpropionate with an assay of 97% and an optical purity of ee: 99%. We do not represent this product as USP, BP, or EP grade.
How should (–)-Methyl (S)-3-bromo-2-methylpropionate be handled safely?
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This compound is a warning hazard, causing skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, should be used. Always consult the Safety Data Sheet before handling.
Is (–)-Methyl (S)-3-bromo-2-methylpropionate a controlled substance?
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There is no information in the provided data to suggest that (–)-Methyl (S)-3-bromo-2-methylpropionate is a controlled substance.
How is (–)-Methyl (S)-3-bromo-2-methylpropionate packed and shipped?
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Tech Serve Solutions exports fine chemicals globally, adhering to all necessary shipping and handling regulations for hazardous materials. Specific packing details are available upon request.
How can I request a quote or sample for (–)-Methyl (S)-3-bromo-2-methylpropionate?
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To request a quote or sample, please contact our sales department through the website or by phone, providing the product name and CAS number.
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