(−)-Methyl (S)-2-chloropropionate

CAS 73246-45-4CH3CH(Cl)CO2CH3Chemical Synthesis

(−)-Methyl (S)-2-chloropropionate (CAS 73246-45-4), with the molecular formula CH3CH(Cl)CO2CH3 and a molecular weight of 122.55 g/mol, is a chiral ester primarily employed as a starting material in asymmetric synthesis. Its specific stereochemistry makes it valuable for constructing complex chiral molecules, particularly in the pharmaceutical and fine chemical industries. This compound serves as a crucial building block for introducing chiral centres in organic synthesis.

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(−)-Methyl (S)-2-chloropropionate (CH3CH(Cl)CO2CH3) — chemical structure, CAS 73246-45-4; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisChemical SynthesisChiral Building BlocksEstersOrganic Building Blocks

01 /Applications

Asymmetric Synthesis

Utilised as a chiral building block to introduce stereospecificity in the synthesis of complex organic molecules. Its defined stereochemistry is critical for creating enantiomerically pure compounds.

Chemical Synthesis Intermediate

Serves as a versatile intermediate in multi-step organic syntheses. Its reactive chlorine atom and ester functional group allow for various chemical transformations.

Chiral Building Block

Provides a readily available source of chirality for the synthesis of pharmaceuticals and other fine chemicals where stereoisomer control is paramount.

Ester Synthesis

As an ester, it can participate in reactions typical of this functional group, serving as a precursor in ester-based synthetic routes.

02 /Properties

Molecular weight	122.55
Linear formula	CH3CH(Cl)CO2CH3
Assay	99%
Boiling point	80-82 °C/110 mmHg(lit.)
Density	1.143 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.417(lit.)
Optical activity	[α]20/D −26°, neat
Optical purity	ee: 97% (GLC)
Application	Chiral starting material.

03 /Safety & handling

GHS hazard pictogram: Flammable (GHS02) — Flammable

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

GHS hazard pictogram: Health hazard (GHS08) — Health hazard

Warning

Hazard statements

H226Flammable liquid and vapour
H319Causes serious eye irritation
H373May cause damage to organs through prolonged exposure

Precautionary statements

P305IF IN EYES

Protective equipment	Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point	32 °C / 89.6 °F
Transport (UN / ADR)	UN 2933 3 / PGIII
Water hazard class (WGK, DE)	1
Hazard codes (EU)	Xn
Risk statements (R)	10-36-48/22
Safety statements (S)	23-26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

73246-45-4

MDL number

MFCD00062941

PubChem substance

24854845

Beilstein registry

1720589

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (–)-Methyl (S)-2-chloropropionate used for?

(–)-Methyl (S)-2-chloropropionate is used as a chiral starting material and building block in asymmetric synthesis and general chemical synthesis.

What are the CAS number and formula for (–)-Methyl (S)-2-chloropropionate?

The CAS number is 73246-45-4 and the molecular formula is CH3CH(Cl)CO2CH3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (–)-Methyl (S)-2-chloropropionate with an assay of 99% and optical purity (ee) of 97%. TSS does not represent this product as USP, BP, or EP grade.

What are the safety considerations for handling (–)-Methyl (S)-2-chloropropionate?

This compound is flammable (H226) and may cause serious eye irritation (H319) and may cause damage to organs through prolonged or repeated exposure (H373). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, should be used. Handle in a well-ventilated area away from ignition sources.

How is (–)-Methyl (S)-2-chloropropionate packed, shipped, and exported?

Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packaging for the safe transport of chemicals like (–)-Methyl (S)-2-chloropropionate, adhering to international shipping regulations (UN 2933 3 / PGIII).

How can I request a sample or quote for (–)-Methyl (S)-2-chloropropionate?

To request a sample or a quote, please contact the Tech Serve Solutions sales team through our website or by phone, providing the product name and CAS number (73246-45-4).