(−)-Methyl (S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate

CAS 60456-21-5C7H12O4Chemical Synthesis

(−)-Methyl (S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate (CAS 60456-21-5), with the molecular formula C7H12O4 and a molecular weight of 160.17, is a chiral building block. It is crucial in organic synthesis, particularly for constructing complex molecules. Its defined stereochemistry makes it valuable in asymmetric synthesis, notably in the preparation of key subunits for biologically active compounds, such as marine toxins.

IUPAC: α,β-Isopropylidene-L-glyceric acid methyl ester,Methyl α,β-isopropylidene-L-glycerate,Methyl 2,3-O-isopropylidene-L-glycerate
Synonyms: 60456-21-5C7H12O4Methyl 2,3-O-isopropylidene-L-glycerateMethyl α,β-isopropylidene-L-glycerateα,β-Isopropylidene-L-glyceric acid methyl ester

Email us

(−)-Methyl (S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate (C7H12O4) — chemical structure, CAS 60456-21-5; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisChemical SynthesisChiral Building BlocksEstersOrganic Building Blocks

01 /Applications

Chiral Building Block Synthesis

This compound serves as a vital chiral building block in asymmetric synthesis. It is used to construct specific stereochemical centres within target molecules, ensuring the correct enantiomeric form is achieved.

Tetrahydrofuran Subunit Construction

It is employed in the synthesis of the key tetrahydrofuran subunit found in (–)-gymnodimine, a notable marine algal toxin. This application highlights its importance in natural product synthesis.

Organic Synthesis Intermediate

As a versatile intermediate in organic synthesis, it facilitates the introduction of specific functional groups and stereochemistry into a wide range of organic molecules. Its structure is amenable to further chemical transformations.

02 /Properties

Molecular weight	160.17
Empirical formula	C7H12O4
Assay	≥97.0% (sum of enantiomers, GC)
Boiling point	84-86 °C/15 mmHg(lit.)
Density	1.106 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.425(lit.)n20/D 1.426
Optical activity	[α]20/D −10.5±1°, neat
Optical purity	enantiomeric ratio: ≥98.0:2.0 (GC)
Storage temperature	2-8°C
Application	Chiral building block used to make the key tetrahydrofuran subunit of (–)-gymnodimine a marine agal toxin.1

03 /Safety & handling

Protective equipment	Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point	78 °C / 172.4 °F
Transport (UN / ADR)	NA 1993 / PGIII
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

60456-21-5

MDL number

MFCD00066526

PubChem substance

24855396

Beilstein registry

4292352

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (–)-Methyl (S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate used for?

This compound is primarily used as a chiral building block in asymmetric synthesis, notably for constructing the tetrahydrofuran subunit of marine toxins like (–)-gymnodimine.

What is the CAS number and chemical formula for this product?

The CAS number is 60456-21-5, and the molecular formula is C7H12O4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this chemical with an assay of ≥97.0% (sum of enantiomers, GC). We do not represent it as USP, BP, or EP grade.

How should (–)-Methyl (S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate be handled and stored?

Handle with appropriate personal protective equipment including eyeshields and chemical-resistant gloves. Store at 2-8°C to maintain stability. Refer to the safety data sheet for comprehensive handling information.

How is this chemical shipped and exported?

This product is shipped and exported according to relevant regulations, classified under NA 1993 / PGIII. Tech Serve Solutions handles international logistics for fine chemicals.

How can I request a sample or obtain a quote?

To request a sample or obtain a quote for (–)-Methyl (S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate, please contact our sales department through the website or by phone.