Methyl isonicotinate
Methyl isonicotinate (CAS 2459-09-8) is the methyl ester of isonicotinic acid (pyridine-4-carboxylic acid), with the molecular formula C7H7NO2 and a molecular weight of 137.14 g/mol. Supplied at a typical assay of 98%, it is a pyridine-based building block used widely in chemical synthesis. Tech Serve Solutions supplies it as a research and laboratory reagent to pharmaceutical, agrochemical and fine-chemical manufacturers worldwide, serving the query methyl isonicotinate supplier and manufacturer for CAS 2459-09-8.
- Synonyms
- Methyl isonicotinateMethyl pyridine-4-carboxylateIsonicotinic acid methyl esterPyridine-4-carboxylic acid methyl ester4-Pyridinecarboxylic acid methyl esterMethyl 4-pyridinecarboxylate

Pharmaceutical intermediate
Serves as a heterocyclic building block in the synthesis of pyridine-containing active pharmaceutical ingredients and intermediates. The reactive ester group offers a convenient handle for amidation, transesterification and reduction.
Organic and medicinal-chemistry synthesis
Used in research laboratories as a C7 pyridine scaffold for constructing more elaborate molecules. The 4-substituted pyridine ring is a versatile motif in medicinal-chemistry programmes.
Agrochemical research
Pyridine carboxylate esters of this type are employed as starting materials in the preparation of agrochemical candidates. It is typically used as a precursor rather than as a finished product.
Ligand and coordination chemistry
The pyridine nitrogen allows the compound and its derivatives to act as ligands in coordination and catalysis studies. This supports its general use as a fine-chemical research reagent.
| Molecular weight | 137.14 |
|---|---|
| Empirical formula | C7H7NO2 |
| Assay | 98% |
| Boiling point | 207-209 °C(lit.) |
| Density | 1.161 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.512(lit.) |
| Melting point | 8-8.5 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 82 °C / 179.6 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is methyl isonicotinate used for?
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Methyl isonicotinate is used principally as a heterocyclic building block in chemical synthesis. It is a pyridine-4-carboxylic acid methyl ester applied in pharmaceutical, agrochemical and fine-chemical research, where its reactive ester group and 4-substituted pyridine ring serve as a versatile synthetic scaffold.
What is the CAS number and molecular formula of methyl isonicotinate?
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Methyl isonicotinate has the CAS number 2459-09-8 and the molecular formula C7H7NO2. Its molecular weight is 137.14 g/mol, the EC number is 219-546-8, the MDL number is MFCD00006427, and the Beilstein registry number is 114618.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies methyl isonicotinate at a typical assay of 98%, as a research and laboratory reagent grade. We do not represent this material as USP, BP or EP pharmacopoeia grade. A certificate of analysis is provided with each consignment, and full specifications are available on request.
What are the safety and handling requirements for methyl isonicotinate?
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Methyl isonicotinate is classified under GHS07 with the signal word Warning. The hazard statements are H315 (causes skin irritation), H319 (causes serious eye irritation) and H335 (may cause respiratory irritation). Handle with gloves and eye protection, use adequate ventilation or respiratory protection, and avoid breathing dust, mist or vapour. It is a combustible liquid with a flash point of about 82 °C. Always consult the Safety Data Sheet before use.
How is methyl isonicotinate packed, shipped and exported?
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The product is packed in suitable sealed containers sized to order and labelled in line with GHS requirements. For transport it is assigned NA 1993, Packing Group III. Tech Serve Solutions exports worldwide with full documentation, including a certificate of analysis and Safety Data Sheet; packaging and shipping mode are confirmed at the quotation stage.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, purity and destination, and our team will respond with availability, lead time and a formal quotation. Samples can be arranged for evaluation, subject to applicable handling and shipping requirements.
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