Methyl 3-(methylthio)propionate
Methyl 3-(methylthio)propionate (CAS: 13532-18-8) is an organic ester with the linear formula CH₃SCH₂CH₂COOCH₃ and a molecular weight of 134.20 g/mol. It is a valuable building block and carbonyl compound utilised in various chemical synthesis applications. This ester is primarily employed in research settings for preparing specific acids and studying biochemical pathways, particularly those involving sulfur-containing compounds and amino acid metabolism.
- IUPAC
- Methyl 3-(methylmercapto)propionate

Preparation of Sulfur-Containing Acids
Methyl 3-(methylthio)propionate serves as a precursor for synthesising 3-(Methylthio)propionic acid. This acid is instrumental in studies investigating the metabolic pathways of amino acids like methionine.
Biochemical Pathway Research
This compound is used in research to prepare intermediates such as 3-methiolpropionate (MMPA). These studies often focus on enzymatic demethylation processes and the degradation of sulfur-containing organic molecules by microorganisms.
Organic Synthesis Intermediate
As a functionalised ester and a C2-C5 building block, Methyl 3-(methylthio)propionate finds application in broader organic synthesis for constructing more complex molecules.
| Molecular weight | 134.20 |
|---|---|
| Linear formula | CH3SCH2CH2COOCH3 |
| Assay | 98% |
| Boiling point | 74-75 °C/13 mmHg(lit.) |
| Density | 1.077 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.465(lit.) |
| Application | Methyl 3-(methylthio)propionate was used to prepare 3-methiolpropionate(MMPA) to study the demethylation of Dimethylsulfoniopropionate and MMPA to 3-mercaptopropionate by aerobic marine bacterium1. Methyl 3-(methylthio)propionate was used to prepare 3-(Methylthio)propionic acid to examine the methionine catabolism by Lactococci by 13C Nuclear Magnetic Resonance and Gas Chromatography2. |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 72 °C / 161.6 °F |
| Transport (UN / ADR) | UN 3334 |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl 3-(methylthio)propionate used for?
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Methyl 3-(methylthio)propionate is primarily used as a building block in organic synthesis and for preparing sulfur-containing acids like 3-(Methylthio)propionic acid. It is also employed in biochemical research to study metabolic pathways involving sulfur compounds and amino acid catabolism.
What is the CAS number and formula for Methyl 3-(methylthio)propionate?
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The CAS number is 13532-18-8, and the linear formula is CH₃SCH₂CH₂COOCH₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl 3-(methylthio)propionate with an assay of 98%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated.
How should Methyl 3-(methylthio)propionate be handled safely?
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Handle with appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (half-mask respirator or multi-purpose combination cartridge recommended). Refer to the Safety Data Sheet for detailed hazard information and handling procedures. It has a flash point of 72 °C (161.6 °F).
Does Tech Serve Solutions export Methyl 3-(methylthio)propionate?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Methyl 3-(methylthio)propionate.
How can I request a sample or quote for Methyl 3-(methylthio)propionate?
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Please contact our sales team through the website or by phone to request a sample or a formal quotation for Methyl 3-(methylthio)propionate.
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