Methyl 3-(dimethylamino)propionate
Methyl 3-(dimethylamino)propionate (CAS: 3853-06-3) is a chemical compound with the linear formula (CH3)2NCH2CH2CO2CH3 and a molecular weight of 131.17 g/mol. This ester serves as a valuable building block in organic synthesis. It is primarily utilised in chemical research and development, particularly for constructing more complex molecules and intermediates. Its physical properties include a boiling point of 152-154 °C and a density of 0.917 g/mL at 25 °C.
Organic Synthesis Intermediate
Methyl 3-(dimethylamino)propionate functions as a versatile building block in organic chemistry. It is employed in reactions requiring a propionate ester with a pendant dimethylamino group.
Reagent for Enolate Formation
This compound has been documented for use in the synthesis of lithium enolates, facilitated by reagents such as lithium diisopropylamide. This application is crucial in stereoselective synthesis.
Research and Development
Utilised in laboratories for fundamental chemical research and the development of novel synthetic methodologies. Its structure lends itself to diverse reaction pathways.
| Molecular weight | 131.17 |
|---|---|
| Linear formula | (CH3)2NCH2CH2CO2CH3 |
| Assay | 99% |
| Boiling point | 152-154 °C(lit.) |
| Density | 0.917 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.418(lit.) |
| Application | Methyl 3-(dimethylamino)propionate was used in the synthesis of lithium enolate via reaction with lithium diisopropylamide1. |
Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 51 °C / 123.8 °F |
| Transport (UN / ADR) | UN 3272 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 16-26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl 3-(dimethylamino)propionate used for?
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Methyl 3-(dimethylamino)propionate is used as a building block in organic synthesis and has been employed in the formation of lithium enolates.
What is the CAS number and formula for Methyl 3-(dimethylamino)propionate?
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The CAS number is 3853-06-3 and the linear formula is (CH3)2NCH2CH2CO2CH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl 3-(dimethylamino)propionate with a purity of 99%. We do not represent this product as USP, BP, or EP grade.
How should Methyl 3-(dimethylamino)propionate be handled safely?
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Methyl 3-(dimethylamino)propionate is a flammable liquid and vapour (H226), causes skin irritation (H315), and serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area.
How is Methyl 3-(dimethylamino)propionate packed, shipped, and exported?
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As a global supplier and exporter, Tech Serve Solutions adheres to all relevant regulations for the packing, shipping, and exporting of chemical products like Methyl 3-(dimethylamino)propionate.
How can I request a sample or quote for Methyl 3-(dimethylamino)propionate?
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To request a sample or a quotation for Methyl 3-(dimethylamino)propionate, please contact our sales department via the website or by phone.
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