Methyl 2-chloroacetimidate hydrochloride
Methyl 2-chloroacetimidate hydrochloride (CAS 70737-12-1) is an organic chemical compound and a hydrochloride salt of methyl chloroacetimidate. It functions as a versatile reactant in organic synthesis. Its primary utility lies in its role as a building block for constructing more complex molecular architectures, particularly in the synthesis of chiral ligands and heterocyclic compounds. This chemical is supplied by TSS for research and development purposes.
- IUPAC
- 2-Chloroethanimidic acid methyl ester hydrochloride,Methyl chloroacetimidate hydrochloride
- Synonyms
- 2-Chloroethanimidic acid methyl ester hydrochlorideMethyl chloroacetimidate hydrochloride

Chiral Ligand Synthesis
Used as a reactant in the modular synthesis of chiral homo- and heterotrisoxazolines, which serve as chiral ligands in asymmetric Michael addition reactions.
Heterocyclic Compound Preparation
Employed in the preparation of benzothiazolylthio oxadiazoles, contributing to the synthesis of diverse heterocyclic structures.
Organic Synthesis Building Block
Serves as a valuable intermediate and building block in general organic chemical synthesis, particularly for nitrogen-containing compounds.
| Molecular weight | 144.00 |
|---|---|
| Linear formula | C3H6ClNO · HCl |
| Storage temperature | −20°C |
| Application | Reactant for:• Modular synthesis of chiral homo- and heterotrisoxazolines as chiral ligands in the asymmetrical Michael addition of indole to benzylidenemalonate1• Preparation of benzothiazolylthio oxadiazoles2 |
| Melting point | 77-82 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl 2-chloroacetimidate hydrochloride used for?
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It is used as a reactant in the synthesis of chiral ligands for asymmetric reactions and in the preparation of heterocyclic compounds like benzothiazolylthio oxadiazoles.
What is the CAS number and formula for Methyl 2-chloroacetimidate hydrochloride?
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The CAS number is 70737-12-1, and its linear formula is C3H6ClNO · HCl.
What is the typical purity or grade of this product?
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This product is supplied for research and chemical synthesis purposes and is not represented as USP, BP, EP, food, or nutraceutical grade.
What are the main hazards associated with Methyl 2-chloroacetimidate hydrochloride?
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It is classified as a Warning substance, with hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation).
How is Methyl 2-chloroacetimidate hydrochloride shipped or exported?
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As a global supplier, TSS handles the export of this chemical, adhering to all relevant shipping and customs regulations.
How can I request a quote for Methyl 2-chloroacetimidate hydrochloride?
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To request a quote, please contact our sales department directly through the TSS website or by phone.
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