Methyl 2-chloro-α-cyanohydrocinnamate
Methyl 2-chloro-α-cyanohydrocinnamate (CAS: 7346-46-5) is an organic compound with the molecular formula ClC6H4CH2CH(CN)CO2CH3 and a molecular weight of 223.66 g/mol. This chemical serves as a valuable building block in organic synthesis, particularly in the creation of more complex molecules. Its structure, featuring a chlorinated phenyl ring, a cyano group, and an ester, offers versatile reactivity for various chemical transformations. It is supplied by TSS for research and development purposes.

Organic Synthesis Intermediate
Serves as a key intermediate in multi-step organic synthesis pathways, enabling the construction of complex molecular architectures.
Pharmaceutical Research
Used as a building block in the research and development of novel pharmaceutical agents and active pharmaceutical ingredients (APIs).
Chemical Synthesis Reagent
Employed in academic and industrial laboratories for exploring new chemical reactions and developing synthetic methodologies.
| Molecular weight | 223.66 |
|---|---|
| Linear formula | ClC6H4CH2CH(CN)CO2CH3 |
| Assay | 99% |
| Boiling point | 126-127 °C/0.75 mmHg(lit.) |
| Melting point | 55-57 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl 2-chloro-α-cyanohydrocinnamate used for?
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Methyl 2-chloro-α-cyanohydrocinnamate is primarily used as a building block and intermediate in organic synthesis, particularly in pharmaceutical research and chemical synthesis laboratories.
What are the CAS number and molecular formula for Methyl 2-chloro-α-cyanohydrocinnamate?
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The CAS number is 7346-46-5, and the molecular formula is ClC6H4CH2CH(CN)CO2CH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl 2-chloro-α-cyanohydrocinnamate with a purity of 99%. This product is intended for research and technical applications and is not represented as USP, BP, or EP grade.
What are the main safety concerns when handling this chemical?
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This compound is classified as harmful if swallowed, in contact with skin, or if inhaled, and causes skin and serious eye irritation. It may also cause respiratory irritation. Always handle with appropriate personal protective equipment, including dust masks (N95), eyeshields, and gloves, in a well-ventilated area.
Can Tech Serve Solutions export this chemical?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals and can arrange shipment to your location.
How can I request a sample or quote for Methyl 2-chloro-α-cyanohydrocinnamate?
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To request a sample or a quotation, please contact the Tech Serve Solutions sales team through our website or by phone, providing your contact details and the product's CAS number (7346-46-5).
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