Methyl 2-bromopropionate
Methyl 2-bromopropionate (CAS 5445-17-0) is an organic ester with the linear formula CH3CHBrCO2CH3 and a molecular weight of 167.00 g/mol. This compound is primarily utilised as a versatile building block in organic synthesis. Its applications span the creation of advanced materials, including polymer brushes, and serve as a key intermediate in the development of radiolabelled imaging agents for medical diagnostics.
Polymer Synthesis
Methyl 2-bromopropionate functions as an initiator in the synthesis of polymer brushes. These polymers are specifically designed to have single-walled carbon nanotubes as their backbones, enabling the creation of novel composite materials.
Medical Imaging Agents
This compound is a crucial starting reagent for synthesising 2-18F-fluoropropionic acid. This radiolabelled molecule serves as a positron emission tomography (PET) imaging agent, particularly for the diagnosis of prostate cancer.
Organic Synthesis Intermediate
As a readily available organic building block, Methyl 2-bromopropionate facilitates various chemical transformations. It is valuable in the preparation of more complex organic molecules for research and development purposes.
| Molecular weight | 167.00 |
|---|---|
| Linear formula | CH3CHBrCO2CH3 |
| Assay | 98% |
| Boiling point | 51 °C/19 mmHg(lit.) |
| Density | 1.497 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.451(lit.) |
| Solubility | water: insoluble |
| Application | Methyl 2-bromopropionate was used as initiator during the synthesis of polymer brushes with single-walled carbon nanotubes as backbones1. It was used as starting reagent for the synthesis of 2-18F-fluoropropionic acid, positron emission tomography imaging agent for prostate cancer2. |
Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 52 °C / 125.6 °F |
| Transport (UN / ADR) | UN 2920 3(8) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-34-36/37 |
| Safety statements (S) | 16-26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl 2-bromopropionate used for?
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Methyl 2-bromopropionate is used as an initiator in polymer synthesis and as a starting reagent for radiolabelled medical imaging agents like 2-18F-fluoropropionic acid.
What is the CAS number and chemical formula for Methyl 2-bromopropionate?
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The CAS number is 5445-17-0, and the linear chemical formula is CH3CHBrCO2CH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl 2-bromopropionate with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should Methyl 2-bromopropionate be handled safely?
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Methyl 2-bromopropionate is a dangerous substance, indicated by GHS02, GHS05, and GHS07 symbols, with a Danger signal word. It is flammable and causes severe skin burns and eye damage, and may cause respiratory irritation. Appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, must be used in a well-ventilated area.
Is Methyl 2-bromopropionate available for export?
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Yes, Tech Serve Solutions specialises in the global supply and export of fine chemicals like Methyl 2-bromopropionate.
How can I obtain a quote or sample?
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Please contact our sales team directly through our website or by phone to request a quotation or arrange for a product sample.
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