Methyl 2,6-dichloropyridine-3-carboxylate
Methyl 2,6-dichloropyridine-3-carboxylate (CAS 65515-28-8) is a halogenated heterocyclic compound with the molecular formula C7H5Cl2NO2 and a molecular weight of 206.03 g/mol. This chemical serves as a valuable building block in organic synthesis, particularly in the field of chemical synthesis. Its structure lends itself to further functionalisation, enabling the creation of more complex molecules. Primarily utilised in research and development settings, it is a key intermediate for creating novel compounds.
- IUPAC
- Methyl 2,6-dichloronicotinate
- Synonyms
- C7H5Cl2NO2Methyl 2,6-dichloronicotinate

Halogenated Heterocycle Synthesis
Serves as a precursor in the synthesis of various halogenated pyridine derivatives. These compounds are often investigated for their potential biological activities or as intermediates in the production of agrochemicals and pharmaceuticals.
Organic Synthesis Building Block
Utilised as a functionalised pyridine core for constructing complex organic molecules. The presence of two chlorine atoms and an ester group allows for diverse chemical transformations and coupling reactions.
Fluorination Reactions
Investigated for its role in nucleophilic aromatic substitution reactions, particularly in the replacement of chloride groups with fluorides using specific reagent systems.
| Molecular weight | 206.03 |
|---|---|
| Empirical formula | C7H5Cl2NO2 |
| Assay | 97% |
| Application | Replacement of chlorides with fluorides using anhydrous nucleophilic fluoride salts generated from potassium fluoride and an arene transfer agent.1 |
| Melting point | 56-60 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl 2,6-dichloropyridine-3-carboxylate used for?
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Methyl 2,6-dichloropyridine-3-carboxylate is primarily used as a building block in organic synthesis, particularly for creating halogenated heterocyclic compounds and in research for developing novel chemical entities.
What is the CAS number and formula for Methyl 2,6-dichloropyridine-3-carboxylate?
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The CAS number is 65515-28-8, and the empirical formula (Hill notation) is C7H5Cl2NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with a minimum assay of 97%. We do not represent it as USP, BP, or EP grade.
How should Methyl 2,6-dichloropyridine-3-carboxylate be handled?
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This compound is a Warning chemical (GHS07). It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used. Handle in a well-ventilated area.
How is this chemical packed and shipped?
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Tech Serve Solutions packages and exports chemicals in compliance with international shipping regulations. Specific packaging details are available upon request.
How can I request a sample or quote?
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To request a sample or a quotation, please use the contact form on our website or contact our sales team directly with your requirements.
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