Methyl 1-chloro-4-hydroxyisoquinoline-3-carboxylate
Methyl 1-chloro-4-hydroxyisoquinoline-3-carboxylate (CAS: 223388-20-3) is a halogenated heterocyclic compound with the molecular formula C11H8ClNO3 and a molecular weight of 237.64 g/mol. It serves as a valuable building block in organic synthesis, particularly within the realm of chemical and pharmaceutical research. This intermediate is utilised for the construction of more complex molecular architectures.

Organic Synthesis Intermediate
This compound is employed as a key intermediate in the synthesis of novel organic molecules. Its halogenated isoquinoline core allows for diverse chemical transformations.
Pharmaceutical Research
Utilised in the development of potential pharmaceutical agents, where the isoquinoline scaffold is a common motif in biologically active compounds.
Heterocyclic Chemistry
Serves as a versatile building block for constructing complex halogenated heterocyclic systems, offering pathways to new chemical entities.
| Molecular weight | 237.64 |
|---|---|
| Empirical formula | C11H8ClNO3 |
| Assay | 97% |
| Melting point | 164-168 °C |

Hazard statements
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl 1-chloro-4-hydroxyisoquinoline-3-carboxylate used for?
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Methyl 1-chloro-4-hydroxyisoquinoline-3-carboxylate is used as a building block and intermediate in organic synthesis, particularly in pharmaceutical research and heterocyclic chemistry.
What is the CAS number and formula for this chemical?
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The CAS number is 223388-20-3 and the empirical formula (Hill notation) is C11H8ClNO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical at a purity of 97%. We do not represent it as USP, BP, EP or other pharmacopoeia grades.
How should Methyl 1-chloro-4-hydroxyisoquinoline-3-carboxylate be handled safely?
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This compound is classified as Danger (GHS05) and causes serious eye damage (H318). Handle with care, using a dust mask (type N95 US), eyeshields, and gloves. Avoid contact with eyes and ensure adequate ventilation. Refer to the Safety Data Sheet for full handling information.
How is this chemical packed and shipped by TSS?
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As a global supplier and exporter, Tech Serve Solutions ensures appropriate packaging and adheres to all regulations for the safe export of this chemical worldwide.
How can I request a sample or quote for Methyl 1-chloro-4-hydroxyisoquinoline-3-carboxylate?
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To request a sample or quote, please use the contact form on our website or call our sales team directly. Provide the product name and CAS number for efficient processing.
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