α-Methoxy-α-(trifluoromethyl)phenylacetonitrile
α-Methoxy-α-(trifluoromethyl)phenylacetonitrile (CAS 80866-87-1) is a specialized organic compound with the molecular formula C₆H₅C(OCH₃)(CF₃)CN and a molecular weight of 215.17 g/mol. It functions as a valuable building block in chemical synthesis. Its structure, featuring a trifluoromethyl group and a nitrile moiety, makes it useful for introducing specific functionalities in complex molecule construction.
Organic Synthesis Intermediate
This compound serves as a key intermediate in various organic synthesis pathways. Its unique combination of functional groups allows for diverse chemical transformations, aiding in the creation of novel molecular architectures.
Fluorinated Building Block
As a source of the trifluoromethyl group, it is employed in the synthesis of fluorinated organic compounds. Fluorine incorporation can significantly alter the physical and biological properties of molecules.
Nitrile Chemistry
The presence of the nitrile group enables further derivatisation, such as hydrolysis to carboxylic acids or reduction to amines, expanding its utility in synthetic chemistry.
| Molecular weight | 215.17 |
|---|---|
| Linear formula | C6H5C(OCH3)(CF3)CN |
| Assay | 98% |
| Boiling point | 76-82 °C/12 mmHg(lit.) |
| Density | 1.152 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.444(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 67 °C / 152.6 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 23-26-28-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is α-Methoxy-α-(trifluoromethyl)phenylacetonitrile used for?
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α-Methoxy-α-(trifluoromethyl)phenylacetonitrile is primarily used as a building block in organic synthesis and as an intermediate for creating fluorinated organic compounds and nitriles.
What is the CAS number and molecular formula for this compound?
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The CAS number is 80866-87-1, and the molecular formula is C₆H₅C(OCH₃)(CF₃)CN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of 98%. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade.
How should α-Methoxy-α-(trifluoromethyl)phenylacetonitrile be handled safely?
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This compound is classified with GHS07, signal word Warning, and hazards H302, H312, H332 (Harmful if swallowed, in contact with skin, or if inhaled). Use appropriate personal protective equipment including eyeshields, gloves, and a suitable respirator. Handle in a well-ventilated area.
Can Tech Serve Solutions export this chemical?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I request a sample or quote?
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Please contact our sales team via the website or direct enquiry channels to request a sample or a quotation for α-Methoxy-α-(trifluoromethyl)phenylacetonitrile.
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