α-Ketoglutaric acid
Alpha-Ketoglutaric acid (CAS 328-50-7) is a vital organic compound with the linear formula HOOCCH₂CH₂COCOOH and a molecular weight of 146.10 g/mol. This white crystalline solid functions as a key intermediate in the Krebs cycle and plays a role in amino acid metabolism. Its chemical structure, featuring both keto and carboxylic acid functionalities, makes it a versatile building block in organic synthesis, particularly for pharmaceuticals and fine chemicals.
- IUPAC
- 2-Oxoglutaric acid,2-Oxopentanedioic acid,alpha-Ketoglutaric acid
- Synonyms
- 2-Oxoglutaric acid2-Oxopentanedioic acidalpha-Ketoglutaric acid
Organic Synthesis
Utilised as a fundamental building block in the synthesis of complex organic molecules. Its dicarboxylic and keto functionalities allow for diverse chemical transformations.
Biochemical Research
Serves as a crucial intermediate in metabolic pathways, particularly the citric acid cycle. It is often used in studies related to cellular respiration and energy production.
Cell Culture Media
Suitable for cell culture and specifically for insect cell culture applications. It provides essential metabolic support for cellular growth and maintenance.
| Molecular weight | 146.10 |
|---|---|
| Linear formula | HOOCCH2CH2COCOOH |
| Assay | ≥99.0% (T) |
| Solubility | H2O: soluble0.1 g/mL, clear, colorless |
| Storage temperature | 2-8°C |
| Suitability | suitable for cell culturesuitable for insect cell culture |
| Melting point | 114-117 °C |
Hazard statements
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 37/38-41 |
| Safety statements (S) | 26-39 |
| Ignition residue | ≤0.05% |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Quality Level | PREMIUM |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Alpha-Ketoglutaric acid used for?
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Alpha-Ketoglutaric acid is used as a building block in organic synthesis and biochemical research, and it is suitable for cell culture applications, including insect cell culture.
What is the CAS number and formula for Alpha-Ketoglutaric acid?
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The CAS number is 328-50-7 and the linear formula is HOOCCH₂CH₂COCOOH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Alpha-Ketoglutaric acid with an assay of ≥99.0% (T), classified as PREMIUM quality. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for Alpha-Ketoglutaric acid?
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Alpha-Ketoglutaric acid is classified as Danger, causing skin irritation (H315), serious eye damage (H318), and respiratory irritation (H335). Users must wear eye shields, gloves, and a type N95 dust mask. Handle in a well-ventilated area and avoid dust formation.
How is Alpha-Ketoglutaric acid packed and exported?
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Alpha-Ketoglutaric acid is carefully packed to ensure stability during transport and is exported globally by Tech Serve Solutions. Specific packaging details are available upon request.
How can I request a quote or sample for Alpha-Ketoglutaric acid?
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To request a quote or a sample of Alpha-Ketoglutaric acid, please contact our sales team via the website or by phone. Details of your required quantity will assist us in processing your request efficiently.
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