Mandelonitrile
Mandelonitrile (CAS 532-28-5), with the molecular formula C6H5CH(OH)CN and a molecular weight of 133.15 g/mol, is an organic compound characterised by both a hydroxyl and a nitrile functional group attached to the same benzylic carbon. It serves as a versatile building block in chemical synthesis, particularly in the creation of more complex organic molecules. Its properties make it a useful intermediate in various laboratory and industrial chemical processes.
- IUPAC
- α-Hydroxyphenylacetonitrile,Benzaldehyde cyanohydrin,Mandelic acid nitrile
- Synonyms
- α-HydroxyphenylacetonitrileBenzaldehyde cyanohydrinMandelic acid nitrile
Chemical Synthesis Intermediate
Mandelonitrile is employed as a key intermediate in organic synthesis. Its dual functionality allows for diverse chemical transformations, enabling the construction of complex molecular architectures.
Nitrilase Variant Research
This compound has been utilised in research concerning nitrilase enzymes. Specifically, it has been used to extract mandeloamide through the action of specific nitrilase variants, contributing to biocatalysis studies.
Organic Building Block
As an organic building block, mandelonitrile is valuable for introducing specific functional groups and structural motifs into target molecules. It is part of the C8 to C9 carbon range for synthetic applications.
| Molecular weight | 133.15 |
|---|---|
| Linear formula | C6H5CH(OH)CN |
| Grade | technical grade |
| Boiling point | 170 °C(lit.) |
| Density | 1.117 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.530(lit.) |
| Solubility | alcohol: freely solublechloroform: freely solublediethyl ether: freely soluble |
| Application | Mandelonitrile has been used to extract mandeloamide by the nitrilase variants1. |
Hazard statements
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H318Causes serious eye damage
- H331Toxic if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 97 °C / 206.6 °F |
| Transport (UN / ADR) | UN 3276 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/24/25-41 |
| Safety statements (S) | 22-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Mandelonitrile used for?
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Mandelonitrile is used as a building block in chemical synthesis and has been utilised in research involving nitrilase variants for extracting compounds like mandeloamide.
What are the CAS number and formula for Mandelonitrile?
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The CAS number for Mandelonitrile is 532-28-5, and its linear formula is C6H5CH(OH)CN.
What grade and purity does Tech Serve Solutions supply for Mandelonitrile?
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Tech Serve Solutions supplies Mandelonitrile in technical grade. We do not represent this product as USP, BP, or EP grade, as this is not explicitly stated in the product data.
What are the primary safety concerns when handling Mandelonitrile?
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Mandelonitrile is classified with Danger (GHS05, GHS06) signal word, presenting hazards H301 (Toxic if swallowed), H311 (Toxic in contact with skin), H318 (Causes serious eye damage), and H331 (Toxic if inhaled). Appropriate personal protective equipment, including eyeshields, face shields, and respiratory protection, is essential.
How is Mandelonitrile packed, shipped, and exported by TSS?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Mandelonitrile. Products are carefully packed to ensure integrity during transit and are exported in compliance with international regulations.
How can I request a quote or sample of Mandelonitrile?
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To request a quote or sample of Mandelonitrile, please contact the Tech Serve Solutions sales team through the website or designated contact channels.
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