Lonidamine
Lonidamine (CAS: 50264-69-2, C15H10Cl2N2O2) is a chemical compound with a molecular weight of 321.16 g/mol. It is primarily recognised for its role in biochemical research, particularly concerning cellular metabolism and cancer research. Lonidamine is known to inhibit hexokinase and affect processes like aerobic glycolysis, making it a valuable tool for scientists studying cellular respiration and the Warburg effect. TSS supplies this compound for research purposes.
- IUPAC
- 1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylic acid,Diclondazolic acid
- Synonyms
- 1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylic acidDiclondazolic acid
Cancer Metabolism Research
Lonidamine is utilized to investigate the Warburg effect, a hallmark of cancer cell metabolism characterized by increased aerobic glycolysis. Researchers employ it to study how cancer cells reprogram their energy production pathways.
Cellular Respiration Studies
This compound serves as an inhibitor of hexokinase, a key enzyme in glycolysis. Its application aids in understanding the intricate mechanisms of cellular respiration and energy generation in various cell types.
Biochemical Research Reagent
As a bioactive small molecule, Lonidamine is supplied for general biochemical research. Its specific inhibitory properties make it a useful reagent for exploring cellular signaling and stress responses.
| Molecular weight | 321.16 |
|---|---|
| Empirical formula | C15H10Cl2N2O2 |
Hazard statements
- H302Harmful if swallowed
- H351Suspected of causing cancer
- H360May damage fertility or the unborn child
Precautionary statements
- P201Obtain special instructions before use
- P281Use personal protective equipment as required
- P308IF exposed or concerned
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 60-22-40 |
| Safety statements (S) | 53-22-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Lonidamine (CAS 50264-69-2) used for?
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Lonidamine is used in biochemical and cancer metabolism research, particularly for studying aerobic glycolysis (the Warburg effect) and cellular respiration by inhibiting hexokinase.
What is the CAS number and chemical formula for Lonidamine?
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The CAS number for Lonidamine is 50264-69-2, and its chemical formula is C15H10Cl2N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Lonidamine typically as a research-grade chemical. Purity information is available on the Certificate of Analysis. We do not represent this product as USP, BP, or EP grade.
What are the primary safety concerns when handling Lonidamine?
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Lonidamine carries a Danger signal word with hazards including H302 (Harmful if swallowed), H351 (Suspected of causing cancer), and H360 (May damage fertility or the unborn child). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, must be used, and handling should occur in a well-ventilated area or fume hood.
Is Lonidamine a controlled substance?
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The provided data does not indicate that Lonidamine is a controlled or scheduled substance.
How is Lonidamine packed, shipped, and exported?
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Lonidamine is packed securely in compliance with relevant regulations for chemical transport. TSS exports globally, adhering to all international shipping and customs requirements for fine chemicals.
How can I request a sample or quote for Lonidamine?
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To request a sample or a quote for Lonidamine, please contact our sales team through the website or by phone, providing your specific requirements.
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