Lithium tert-amoxide solution
Lithium tert-amoxide solution (CAS: 53535-81-2, C5H11LiO) is a potent organic base supplied by Tech Serve Solutions. With a molecular weight of 94.08 g/mol, this flammable, corrosive, and reactive compound is typically provided as a 40% (w/w) solution in heptanes. It is a valuable reagent in organic synthesis, primarily employed as a strong, non-nucleophilic base for deprotonation reactions and in the preparation of other organometallic reagents.
- IUPAC
- Lithium 2-methyl-2-butoxide,Lithium tert-amylate,Lithium tert-pentoxide,Lithium tert-pentyloxide
- Synonyms
- Lithium 2-methyl-2-butoxideLithium tert-amylateLithium tert-pentoxideLithium tert-pentyloxide
Strong Base in Organic Synthesis
Lithium tert-amoxide serves as a powerful base for deprotonating weakly acidic protons in various organic molecules. Its steric bulk often leads to high regioselectivity in elimination reactions.
Reagent for Organometallic Chemistry
This compound can be used in the synthesis of other lithium organic reagents or in reactions requiring a sterically hindered strong base, facilitating complex synthetic routes.
Deprotonation Reactions
It is particularly useful for the formation of enolates and other carbanions, which are key intermediates in carbon-carbon bond formation reactions like aldol condensations.
| Molecular weight | 94.08 |
|---|---|
| Empirical formula | C5H11LiO |
| Density | 0.73 g/mL at 25 °C |
| Concentration | 40 % (w/w) in heptanes~3.1 M in heptane |
Hazard statements
- H225Highly flammable liquid and vapour
- H260In contact with water releases flammable gases
- H302Harmful if swallowed
- H304May be fatal if swallowed and enters airways
- H314Causes severe skin burns and eye damage
- H331Toxic if inhaled
- H336May cause drowsiness or dizziness
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P223Do not allow contact with water
- P231Handle under inert gas
- P261Avoid breathing dust, fume, gas or vapours
- P370In case of fire
- P422
| Flash point | -9 °C / 15.8 °F |
|---|---|
| Transport (UN / ADR) | UN 3274 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C,N |
| Risk statements (R) | 11-14-20/22-35-50/53-65 |
| Safety statements (S) | 16-26-36/37/39-45-61-62 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Lithium tert-amoxide solution used for?
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Lithium tert-amoxide solution is primarily used as a strong, sterically hindered base in organic synthesis for deprotonation reactions, such as enolate formation, and in the preparation of other organometallic reagents.
What is the CAS number and formula for Lithium tert-amoxide solution?
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The CAS number is 53535-81-2, and the empirical formula is C5H11LiO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Lithium tert-amoxide solution typically as a 40% (w/w) solution in heptanes. We do not represent this product as USP, BP, or EP grade.
How should Lithium tert-amoxide solution be handled?
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Lithium tert-amoxide solution is highly flammable and reactive with water, causing severe skin burns and eye damage. It is toxic if inhaled and can cause respiratory irritation. Handle with extreme caution in a well-ventilated area, away from ignition sources and incompatible materials, using appropriate personal protective equipment. It reacts violently with water.
How is Lithium tert-amoxide solution packed and shipped?
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This product is packed and shipped in accordance with UN 3274 regulations, classified under hazard class 8(3) and packing group II, reflecting its flammable and corrosive nature.
How can I request a sample or quote for Lithium tert-amoxide solution?
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Please contact our sales team via the website or direct email to request a sample or a detailed quotation for Lithium tert-amoxide solution.
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