Lithium tert-butoxide

CAS 1907-33-1(CH3)3COLiAcids & Bases

Lithium tert-butoxide (CAS: 1907-33-1), with the linear formula (CH3)3COLi and a molecular weight of 80.05 g/mol, is a strong, non-nucleophilic organic base. It is frequently employed as a reagent in organic synthesis for deprotonation reactions. Supplied as a 1.0 M solution in THF, it is particularly useful for reactions requiring precise stoichiometric control and high solubility in organic solvents. TSS offers this chemical for research and industrial applications.

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Lithium tert-butoxide ((CH3)3COLi) — chemical structure, CAS 1907-33-1; Chemistry, fine chemical supplied by Tech Serve Solutions

Acids & BasesBasesChemical SynthesisOrganic BasesSynthetic Reagents

01 /Applications

Organic Synthesis Reagent

Lithium tert-butoxide is widely used as a strong, sterically hindered base in organic synthesis. Its non-nucleophilic character makes it ideal for promoting elimination reactions and facilitating deprotonations where nucleophilic attack is undesirable.

Deprotonation Reactions

This reagent serves as an effective base for abstracting acidic protons in various organic molecules. Its bulkiness prevents it from acting as a nucleophile, ensuring selective deprotonation.

Polymerisation Catalyst

In certain polymerisation processes, lithium tert-butoxide can function as an initiator or catalyst, particularly in the synthesis of specific polymers where strong basic conditions are required.

02 /Properties

Molecular weight	80.05
Linear formula	(CH3)3COLi
Assay	≥95% (T)
Boiling point	67 °C
Density	0.888 g/mL at 25 °C
Concentration	1.0 M in THF
Impurities tested	≤3% LiOH and Li2CO3

03 /Safety & handling

GHS hazard pictogram: Flammable (GHS02) — Flammable

GHS hazard pictogram: Corrosive (GHS05) — Corrosive

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Danger

Hazard statements

H251Self-heating; may catch fire
H302Harmful if swallowed
H314Causes severe skin burns and eye damage

Precautionary statements

P235Keep cool
P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES
P310Immediately call a POISON CENTER or doctor

Protective equipment	Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Transport (UN / ADR)	UN 3206 4.2/PG 2
Water hazard class (WGK, DE)	3
Hazard codes (EU)	F,C
Risk statements (R)	11-14-34
Safety statements (S)	7/8-26-33-36/37/39-43-45
Supplemental hazards	Reacts violently with water.

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

1907-33-1

MDL number

MFCD00050479

Beilstein registry

3620018

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Lithium tert-butoxide used for?

Lithium tert-butoxide is primarily used as a strong, non-nucleophilic organic base in various synthetic organic chemistry applications, including deprotonation and elimination reactions.

What is the CAS number and formula for Lithium tert-butoxide?

The CAS number for Lithium tert-butoxide is 1907-33-1, and its linear formula is (CH3)3COLi.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Lithium tert-butoxide with an assay of ≥95% (T), containing ≤3% LiOH and Li2CO3 impurities. We do not represent this product as USP, BP, or EP grade.

How should Lithium tert-butoxide be handled safely?

Lithium tert-butoxide is highly reactive and reacts violently with water, is flammable, corrosive, and harmful if swallowed. Handle with extreme care in a well-ventilated area, using appropriate personal protective equipment including gloves, eye protection, and respiratory protection. Store away from moisture and ignition sources.

How is Lithium tert-butoxide packed and shipped?

Lithium tert-butoxide is typically supplied as a 1.0 M solution in THF. It is classified as UN 3206, Hazard Class 4.2, Packing Group II, and requires specialised handling and shipping procedures suitable for pyrophoric and corrosive materials.

How can I request a sample or quote for Lithium tert-butoxide?

To request a sample or a quote for Lithium tert-butoxide, please contact our sales team via the website or direct telephone line, providing your specific requirements.