LDN-57444
LDN-57444 (CAS: 668467-91-2) is a chemical compound with the molecular formula C17H11Cl3N2O3 and a molecular weight of 397.64 g/mol. This substance is primarily utilized in research settings for its properties related to intracellular protein degradation and cell signaling pathways. Its applications are focused on scientific investigation within cell biology and neuroscience, aiding in the study of cellular stress and the ubiquitin-proteasome system.
- IUPAC
- 3-(O-acetyloxime), 5-chloro-1-[(2,5-dichlorophenyl)methyl]-1H-Indole-2,3-dione,C30,LDN 57444
Intracellular Protein Degradation Research
LDN-57444 is employed in studies investigating the mechanisms of targeted protein degradation within cells. It serves as a tool to understand pathways involved in cellular protein turnover and homeostasis.
Cell Biology Studies
Researchers use LDN-57444 to explore various cellular processes, including cell signaling and the response to cellular stress. Its application aids in dissecting complex biological pathways at the molecular level.
Neuroscience Research
The compound finds application in neuroscience research, particularly in understanding neuronal cell function and responses. Its use can help elucidate the roles of protein degradation in neurological processes.
Ubiquitin-Proteasome System Investigation
LDN-57444 is a valuable reagent for scientists studying the ubiquitin-proteasome system, a critical pathway for protein degradation in eukaryotic cells. It helps in probing the functionality and regulation of this system.
| Molecular weight | 397.64 |
|---|---|
| Empirical formula | C17H11Cl3N2O3 |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Solubility | DMSO: soluble16 mg/mL |
| Storage temperature | 2-8°C |
Hazard statements
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P501Dispose of contents and container per local regulations
| Transport (UN / ADR) | UN 3077 9 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | N |
| Risk statements (R) | 50/53 |
| Safety statements (S) | 60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | desiccatedprotect from light |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is LDN-57444 used for?
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LDN-57444 is used in research for investigating intracellular protein degradation, cell signaling, neuroscience, and the ubiquitin-proteasome system, particularly in the context of cell biology and cellular stress.
What are the CAS number and formula for LDN-57444?
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The CAS number for LDN-57444 is 668467-91-2, and its empirical formula is C17H11Cl3N2O3.
What grade and purity does Tech Serve Solutions supply for LDN-57444?
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Tech Serve Solutions supplies LDN-57444 with a purity of ≥98% as determined by HPLC. This product is intended for research purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should LDN-57444 be handled and stored?
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LDN-57444 is classified under GHS09 and carries the signal word 'Warning', with hazard statement H410. It should be stored desiccated and protected from light at 2-8°C. Handle with appropriate personal protective equipment in a well-ventilated area, following P273 and P501 precautionary statements.
Is LDN-57444 shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including LDN-57444. We handle all necessary export documentation and comply with international shipping regulations.
How can I request a quote or sample for LDN-57444?
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To request a quote or sample for LDN-57444, please visit the product page on our website and use the 'Request Quote' or 'Request Sample' function, or contact our sales team directly.
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