L-741,626
L-741,626 (CAS: 81226-60-0), a white solid with the molecular formula C20H21ClN2O and a molecular weight of 340.85 g/mol, is a selective antagonist. It is primarily utilised in scientific research, particularly within neuroscience and cell biology, for investigating dopaminergic pathways and GPCR modulation. Supplied by Tech Serve Solutions, this compound meets high purity standards for laboratory applications.
- IUPAC
- (±)-3-[4-(4-Chlorophenyl)-4-hydroxypiperidinyl]methylindole
- Synonyms
- 626(±)-3-[4-(4-Chlorophenyl)-4-hydroxypiperidinyl]methylindole
Dopamine Receptor Antagonism Research
L-741,626 acts as a selective antagonist for dopamine receptors, making it a valuable tool for researchers studying dopaminergic neurotransmission and its role in neurological processes. Its use allows for detailed investigation into receptor function and signalling pathways.
GPCR Modulation Studies
As a modulator of G protein-coupled receptors (GPCRs), this compound aids in the study of cellular signalling mechanisms. Researchers employ it to understand how GPCRs are regulated and how their modulation impacts biological functions.
Neuroscience Research Tool
This chemical is instrumental in neuroscience for exploring brain function, neurotransmitter systems, and the development of potential therapeutic strategies for neurological disorders. Its specific action on dopamine receptors is key to these investigations.
Cell Biology Investigations
L-741,626 is applied in cell biology research to examine cellular responses and signalling cascades, particularly those involving dopaminergic systems. It serves as a specific probe to dissect complex cellular interactions.
| Molecular weight | 340.85 |
|---|---|
| Empirical formula | C20H21ClN2O |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | DMSO: ≥20 mg/mLethanol: soluble24 mg/mLH2O: insoluble |
| Storage temperature | room temp |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... DRD2(1813), DRD3(1814), DRD4(1815) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-741,626 used for?
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L-741,626 is primarily used in scientific research as a selective antagonist, particularly for investigating dopaminergic pathways in neuroscience and cell biology, and for studying G protein-coupled receptor (GPCR) modulation.
What are the CAS number and molecular formula for L-741,626?
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The CAS number for L-741,626 is 81226-60-0, and its molecular formula is C20H21ClN2O.
What grade and purity does Tech Serve Solutions supply for L-741,626?
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Tech Serve Solutions supplies L-741,626 with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should L-741,626 be handled and stored?
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When handling L-741,626, it is essential to use appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Store at room temperature.
Is L-741,626 a controlled substance?
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The provided data does not indicate that L-741,626 is a controlled substance.
How is L-741,626 shipped and exported?
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L-741,626 is available for global export from Tech Serve Solutions, a specialist supplier since 1998, in compliance with international shipping regulations for chemicals.
How can I request a sample or quote for L-741,626?
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To request a sample or obtain a quote for L-741,626, please contact Tech Serve Solutions directly through our website or sales department.
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