Isoquinoline-6-boronic acid pinacol ester
Isoquinoline-6-boronic acid pinacol ester (CAS: 675576-26-8; Formula: C15H18BNO2) is a valuable organoboron compound with a molecular weight of 255.12 g/mol. It is primarily utilised as a key building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions. This ester offers a stable and convenient way to introduce the isoquinoline moiety into complex molecular structures, finding applications in medicinal chemistry and materials science.
Suzuki-Miyaura Cross-Coupling Reactions
Isoquinoline-6-boronic acid pinacol ester serves as an effective coupling partner in palladium-catalyzed Suzuki-Miyaura reactions. This enables the formation of carbon-carbon bonds with aryl or vinyl halides, facilitating the synthesis of biaryl compounds and other complex organic molecules.
Medicinal Chemistry Research
The isoquinoline scaffold is present in many biologically active compounds. This boronate ester allows for the precise incorporation of this important heterocycle into novel drug candidates during the discovery and development phases.
Materials Science
As a building block for organic electronics and functional materials, this compound can be employed to construct conjugated systems with specific optoelectronic properties, leveraging the electronic characteristics of the isoquinoline ring.
| Molecular weight | 255.12 |
|---|---|
| Empirical formula | C15H18BNO2 |
| Assay | 95% |
| Storage temperature | 2-8°C |
| Application | Useful boron compound for Suzuki coupling. |
| Melting point | 179-184 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Isoquinoline-6-boronic acid pinacol ester used for?
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Isoquinoline-6-boronic acid pinacol ester is primarily used as a boron compound for Suzuki coupling reactions in organic synthesis, facilitating the introduction of the isoquinoline moiety into complex molecules.
What are the CAS number and molecular formula?
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The CAS number for Isoquinoline-6-boronic acid pinacol ester is 675576-26-8, and its molecular formula is C15H18BNO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Isoquinoline-6-boronic acid pinacol ester with an assay of 95%. We do not represent this product as meeting USP, EP, or BP pharmacopoeia standards.
What are the safety and handling precautions?
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This compound is classified as a Warning with hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Users should avoid breathing dust/fume/gas/mist/vapours/spray and ensure adequate ventilation. Wear protective gloves and eye protection. In case of contact with eyes, rinse cautiously with water for several minutes and seek medical advice if irritation persists.
How is Isoquinoline-6-boronic acid pinacol ester packed and exported?
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This chemical is typically stored at 2-8°C. Tech Serve Solutions ensures appropriate packaging for safe domestic shipment and international export, adhering to all relevant regulations.
How can I request a quote or sample?
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To request a quote or a sample of Isoquinoline-6-boronic acid pinacol ester, please contact our sales team via the website or direct inquiry channels.
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