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Iodomethane

CAS 74-88-4CH3IChemical Synthesis

Iodomethane (CH3I, CAS 74-88-4) is a volatile organoiodine compound with a molecular weight of 141.94 g/mol. Known for its utility as a methylating agent in organic synthesis, it is commonly employed in the preparation of various organic compounds and pharmaceutical intermediates. Supplied by Tech Serve Solutions with an assay of ≥99.0%, this compound is a vital reagent in diverse chemical research and industrial applications.

IUPAC
Methyl iodide
Synonyms
Methyl iodide
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Iodomethane (CH3I) — chemical structure, CAS 74-88-4; Chemistry, fine chemical supplied by Tech Serve Solutions
AlkylBiochemicals and ReagentsBuilding BlocksChemical SynthesisEnzymesInhibitorsand SubstratesHalogenated HydrocarbonsIOD - Iodomethane
01 /Applications

Methylating Agent in Organic Synthesis

Iodomethane serves as a potent electrophilic methylating agent. It is frequently used in SN2 reactions to introduce a methyl group onto nucleophiles, facilitating the synthesis of complex organic molecules and pharmaceutical precursors.

Reagent for Biochemical Studies

This compound is utilised in specific biochemical research, such as its role within the β-Glucuronidase Drug Analysis Bundle. It is also found in applications involving enzymes, inhibitors, and substrates.

Analytical Chemistry Applications

Iodomethane finds application in analytical chemistry, particularly in methods requiring precise methylation for detection or derivatisation of analytes. Its defined purity aids in reproducible analytical results.

Industrial Chemical Synthesis

Beyond laboratory scale, iodomethane is employed in industrial processes requiring efficient methylation for the production of various chemical products. Its high reactivity makes it suitable for large-scale synthesis.

02 /Properties
Molecular weight141.94
Empirical formulaCH3I
Assay≥99.0% (GC)
Gradepurum
Boiling point41-43 °C(lit.)41-43 °C
Density2.28 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.530n20/D 1.531(lit.)
Melting point−64(lit.)
Concentration2.0 M in tert-butyl methyl ether
Vapour pressure24.09 psi (55 °C)7.89 psi (20 °C)
Vapour density4.89 (vs air)
Storage temperature2-8°C
Contains / stabilisersilver wool as stabilizer
Impurities tested≤0.5% CH2I2
03 /Safety & handling
GHS hazard pictogram: Toxic (GHS06)
Toxic
GHS hazard pictogram: Health hazard (GHS08)
Health hazard
Danger

Hazard statements

  • H301Toxic if swallowed
  • H312Harmful in contact with skin
  • H315Causes skin irritation
  • H331Toxic if inhaled
  • H335May cause respiratory irritation
  • H351Suspected of causing cancer

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P280Wear protective gloves, clothing and eye/face protection
  • P301IF SWALLOWED
  • P311Call a POISON CENTER or doctor
Protective equipmentFaceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US)
Transport (UN / ADR)UN 2644 6.1 / PGI
Water hazard class (WGK, DE)3
Hazard codes (EU)T
Risk statements (R)21-23/25-37/38-40
Safety statements (S)36/37-38-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
74-88-4
Beilstein registry
969135
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Iodomethane used for?

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Iodomethane (CH3I) is primarily used as a methylating agent in organic synthesis for introducing methyl groups onto nucleophiles, and in various biochemical and analytical chemistry applications.

What are the CAS number and formula for Iodomethane?

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The CAS number for Iodomethane is 74-88-4, and its chemical formula is CH3I.

What grade and purity does Tech Serve Solutions supply for Iodomethane?

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Tech Serve Solutions supplies Iodomethane with a grade of 'purum' and an assay of ≥99.0% (GC). We do not represent this product as USP, BP, or EP grade unless explicitly stated.

How should Iodomethane be handled and stored?

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Iodomethane is a dangerous substance (Danger signal word) that is toxic if swallowed, in contact with skin, or if inhaled, and can cause skin irritation, respiratory irritation, and is suspected of causing cancer. Handle with appropriate personal protective equipment, including full-face respirators and chemical-resistant gloves, and store at 2-8°C.

Is Iodomethane a controlled substance?

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According to the provided data, Iodomethane is classified under RID/ADR as UN 2644, Hazard Class 6.1, Packing Group I. Its handling and status should be verified against local regulations.

How is Iodomethane packed and exported?

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Iodomethane is exported by Tech Serve Solutions adhering to all relevant shipping and safety regulations for hazardous materials.

How can I request a quote or sample of Iodomethane?

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To request a quote or sample for Iodomethane, please contact the Tech Serve Solutions sales team through our official channels.

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