Imipramine hydrochloride
Imipramine hydrochloride (CAS: 113-52-0), with the molecular formula C19H24N2 · HCl and a molecular weight of 316.87 g/mol, is a dibenzazepine derivative. This white crystalline compound functions as a biogenic amine reuptake inhibitor. It is primarily utilised in research settings for its effects on neurotransmission, serving as a valuable tool in neuroscience and cell signaling studies.
- IUPAC
- 10,11-Dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine hydrochloride,5-[3-(Dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine hydrochloride
- Synonyms
- 5-[3-(Dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine hydrochloride10,11-Dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine hydrochloride

Neuroscience Research
Imipramine hydrochloride is used to investigate the mechanisms of neurotransmitter reuptake and signaling pathways within the central nervous system. It helps researchers understand the roles of serotonin and norepinephrine in various neurological functions and disorders.
Cell Biology Studies
This compound serves as a pharmacological tool in cell biology to explore cellular responses to changes in neurotransmitter levels. Its effects on cell signaling pathways and membrane transport make it relevant for studies involving neuronal cells.
Biochemical Assays
As a bioactive small molecule, imipramine hydrochloride is employed in biochemical assays to study the activity and inhibition of transporter proteins. Its specific interactions provide insights into receptor binding and function.
| Molecular weight | 316.87 |
|---|---|
| Empirical formula | C19H24N2 · HCl |
| Assay | ≥99% (TLC) |
| Form | crystalline |
| Colour | white |
| Solubility | H2O: soluble50 mg/mL |

Hazard statements
- H302Harmful if swallowed
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Imipramine hydrochloride used for?
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Imipramine hydrochloride is used in research for its role as a biogenic amine reuptake inhibitor, particularly in neuroscience and cell biology studies investigating neurotransmission and cell signaling.
What are the CAS number and formula for Imipramine hydrochloride?
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The CAS number for Imipramine hydrochloride is 113-52-0, and its empirical formula is C19H24N2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Imipramine hydrochloride with a purity of ≥99% (TLC). We do not represent this product as USP, BP, or EP grade.
What are the safety considerations for handling Imipramine hydrochloride?
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Imipramine hydrochloride is classified with the GHS07 symbol and has a 'Warning' signal word, indicating it is harmful if swallowed (H302). Handle with appropriate personal protective equipment in a well-ventilated area. WGK classification is 3.
How is Imipramine hydrochloride packed and shipped?
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Imipramine hydrochloride is typically supplied as a white crystalline powder. TSS exports chemicals globally, adhering to all relevant shipping and handling regulations.
How can I request a sample or quote for Imipramine hydrochloride?
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To request a sample or quote, please contact our sales team through the website or by phone, providing the product name and CAS number (113-52-0).
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