1-Ethylbutylzinc bromide solution
1-Ethylbutylzinc bromide solution (CAS 312693-14-4) is an organozinc halide reagent. With the linear formula CH3CH2CH2CH(C2H5)ZnBr and a molecular weight of 230.46, it is supplied as a 0.5 M solution in THF. This compound is primarily utilised in organic synthesis as a source of the 1-ethylbutyl group for carbon-carbon bond formation, fitting within categories such as chemical synthesis and organometallic reagents.
Organozinc Reagent in Synthesis
1-Ethylbutylzinc bromide solution serves as a valuable organometallic reagent for introducing the 1-ethylbutyl moiety into organic molecules. It participates in various coupling reactions and nucleophilic additions, facilitating the construction of complex carbon skeletons.
Cross-Coupling Reactions
This organozinc halide is employed in transition-metal catalysed cross-coupling reactions, such as Negishi couplings. These reactions enable the formation of new carbon-carbon bonds with high selectivity and efficiency.
Nucleophilic Alkylation
The reagent can act as a nucleophile in reactions with electrophilic centres, such as alkyl or acyl halides, and carbonyl compounds. This allows for the direct alkylation of various substrates.
| Molecular weight | 230.46 |
|---|---|
| Linear formula | CH3CH2CH2CH(C2H5)ZnBr |
| Boiling point | 65 °C |
| Density | 0.968 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-14-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Ethylbutylzinc bromide solution used for?
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1-Ethylbutylzinc bromide solution is used as an organometallic reagent in organic synthesis, particularly for introducing the 1-ethylbutyl group via cross-coupling and nucleophilic addition reactions.
What is the CAS number and formula for 1-Ethylbutylzinc bromide solution?
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The CAS number is 312693-14-4 and the linear formula is CH3CH2CH2CH(C2H5)ZnBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Ethylbutylzinc bromide solution at a concentration of 0.5 M in THF. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should 1-Ethylbutylzinc bromide solution be handled?
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1-Ethylbutylzinc bromide solution is flammable and can cause serious eye irritation, respiratory irritation, and is suspected of causing cancer. It may also form explosive peroxides. Handle with appropriate personal protective equipment in a well-ventilated area, away from ignition sources. Refer to the Safety Data Sheet for full details.
Is this chemical controlled or scheduled?
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The provided data does not indicate that this chemical is controlled or scheduled.
How is 1-Ethylbutylzinc bromide solution packed and shipped?
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1-Ethylbutylzinc bromide solution is shipped as UN 2924, Hazard Class 8(3), Packing Group II. TSS handles export documentation and shipping procedures for global customers.
How can I request a quote or sample?
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To request a quote or a sample of 1-Ethylbutylzinc bromide solution, please contact the TSS sales team through the website or by phone, providing your contact details and intended use.
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