Ibudilast
Ibudilast (CAS 50847-11-5), a white solid with the molecular formula C14 H18 N2 O, is a potent phosphodiesterase inhibitor. It is widely recognised for its role in cell signaling and neuroscience research, acting as a key tool in studies related to cyclic nucleotide metabolism. Its ability to modulate cellular pathways makes it valuable in various biological investigations. Tech Serve Solutions supplies Ibudilast for research purposes.
- IUPAC
- 2-Methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl] 1-propanone,3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine,KC-404
- Synonyms
- KC-4043-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine2-Methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl] 1-propanone
Neuroscience Research
Ibudilast serves as a critical reagent in neuroscience, aiding the investigation of cellular signaling pathways and neuroprotective mechanisms. Its phosphodiesterase inhibitory activity is instrumental in understanding neuronal function and dysfunction.
Cell Biology Studies
In cell biology, Ibudilast is employed to study the impact of cyclic nucleotide modulation on cellular processes. It provides researchers with a means to explore the effects of PDE inhibition on various cell types and functions.
Pharmacological Research
As a bioactive small molecule, Ibudilast is utilised in pharmacological research to investigate potential therapeutic targets and mechanisms of action. Its well-defined properties facilitate in-depth study of its biological effects.
| Molecular weight | 230.31 |
|---|---|
| Empirical formula | C14 H18 N2 O |
| Assay | ≥99% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | DMSO: soluble28 mg/mLH2O: soluble4.5 mg/mL |
| Storage temperature | 2-8°C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... PDE4A(5141), PDE4B(5142), PDE4C(5143), PDE4D(5144) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ibudilast primarily used for?
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Ibudilast is primarily used in neuroscience research and cell biology studies as a phosphodiesterase inhibitor to investigate cellular signaling pathways and cyclic nucleotide metabolism.
What are the CAS number and molecular formula for Ibudilast?
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The CAS number for Ibudilast is 50847-11-5, and its molecular formula is C14 H18 N2 O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ibudilast with an assay of ≥99% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should I handle Ibudilast safely?
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Ibudilast is a Warning substance (GHS07) and may cause harm if swallowed, skin irritation, eye irritation, and respiratory irritation (H302-H315-H319-H335). When handling, use a dust mask type N95 (US), wear eyeshields and gloves. Ensure adequate ventilation and avoid breathing dust.
How is Ibudilast typically shipped and exported?
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Ibudilast is typically shipped as a solid in appropriate packaging for research chemicals. Tech Serve Solutions is a global supplier and exporter, adhering to all relevant shipping regulations.
How can I request a quote or sample for Ibudilast?
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To request a quote or a sample for Ibudilast, please contact our sales team through the website or by phone, providing your specific requirements.
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