3-Aminophthalic acid
3-Aminophthalic acid (CAS: 5434-20-8), with the molecular formula H₂NC₆H₃-1,2-(CO₂H)₂, is an aromatic amino acid derivative. It is a key building block in organic synthesis, particularly useful in the preparation of fluorescent probes, dyes, and biologically active molecules. Its structural features allow for diverse chemical modifications, making it a valuable intermediate in chemical biology and peptide chemistry research.
- Synonyms
- 2-(Carboxy)aniline-3-carboxylic acid3-Amino-1,2-benzenedicarboxylic acid

Chemical Synthesis
Serves as a versatile intermediate for the synthesis of complex organic molecules. Its amino and carboxylic acid functionalities enable a range of reactions, including amide formation and cyclization.
Fluorescent Probe Development
Used in the design and synthesis of fluorescent labels and probes due to its potential for generating luminescent compounds upon derivatization or incorporation into larger systems.
Peptide and Unnatural Amino Acid Chemistry
Incorporated as an unnatural amino acid derivative to modify peptide structures, influencing their properties or creating novel biochemical tools for research.
Dye and Pigment Precursor
Acts as a precursor in the synthesis of various dyes and pigments, leveraging its aromatic structure for chromophore development.
| Molecular weight | 181.15 |
|---|---|
| Linear formula | H2NC6H3-1,2-(CO2H)2 |
| Assay | 90% |
| Melting point | 180-185 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Aminophthalic acid used for?
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3-Aminophthalic acid is primarily used in chemical synthesis, as a precursor for dyes and fluorescent probes, and in peptide and unnatural amino acid chemistry.
What are the CAS number and molecular formula for 3-Aminophthalic acid?
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The CAS number is 5434-20-8 and the molecular formula is H₂NC₆H₃-1,2-(CO₂H)₂.
What grade and purity does Tech Serve Solutions supply for 3-Aminophthalic acid?
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Tech Serve Solutions supplies 3-Aminophthalic acid with an assay of 90%. We do not represent this product as USP, BP, or EP grade.
How should 3-Aminophthalic acid be handled safely?
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3-Aminophthalic acid is classified as a Warning. It can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation and avoid dust formation.
How is 3-Aminophthalic acid packed and shipped?
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Tech Serve Solutions exports fine chemicals globally. Specific packaging details are available upon request, adhering to international shipping regulations.
How can I request a sample or quote for 3-Aminophthalic acid?
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Please contact our sales team via the website or direct email to request a sample or a formal quotation for 3-Aminophthalic acid.
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