3-Aminophenylboronic acid monohydrate
3-Aminophenylboronic acid monohydrate (CAS: 206658-89-1; Formula: H₂NC₆H₄B(OH)₂ · H₂O; MW: 154.96) is a versatile organoborane compound supplied by Tech Serve Solutions. This white to off-white solid serves as a key reagent in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. Its applications extend to the preparation of novel drug candidates, including antivirulence agents and sedative analogues, as well as advanced materials like glucose-sensitive polymers.
- IUPAC
- 3-Aminobenzeneboronic acid
- Synonyms
- 3-Aminobenzeneboronic acid
Suzuki-Miyaura Cross-Coupling Reactions
Serves as a valuable building block in palladium-catalyzed Suzuki-Miyaura cross-coupling reactions for the synthesis of complex organic molecules.
Preparation of Antiviral Agents
Utilised in the synthesis of gram-positive antivirulence drugs and inhibitors targeting specific bacterial pathogens like *Streptococcus agalactiae*.
Synthesis of Pharmaceutical Intermediates
A key intermediate in the preparation of regioisomers of pharmaceutical compounds, such as the sedative Zaleplon.
Development of Advanced Polymers
Employed in the creation of amphiphilic random glycopolymer nanoparticles and chemomechanical polymers with applications in glucose sensing and drug delivery.
| Molecular weight | 154.96 |
|---|---|
| Linear formula | H2NC6H4B(OH)2 · H2O |
| Assay | 98% |
| Application | Reagent used for• Suzuki-Miyaura cross-coupling1 Reagent used for Preparation of• Gram-positive antivirulence drugs and inhibitors of Streptococcus agalactiae Stk12• Regioisomer of Zaleplon (a sedative)1• Amphiphilic random glycopolymer, which self-assemble to form nanoparticles, with potential as a glucose-sensitive matrix3 • Chemomechanical polymer that expands and contracts in blood plasma with high glucose selectivity4 |
| Melting point | 93-96 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What are the primary uses of 3-Aminophenylboronic acid monohydrate?
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3-Aminophenylboronic acid monohydrate is primarily used as a reagent in Suzuki-Miyaura cross-coupling reactions and for the preparation of antivirulence drugs, sedative analogues, and glucose-sensitive polymers.
What are the CAS number and formula for 3-Aminophenylboronic acid monohydrate?
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The CAS number is 206658-89-1 and the formula is H₂NC₆H₄B(OH)₂ · H₂O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Aminophenylboronic acid monohydrate with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 3-Aminophenylboronic acid monohydrate be handled safely?
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3-Aminophenylboronic acid monohydrate is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, in a well-ventilated area.
Is 3-Aminophenylboronic acid monohydrate exported by Tech Serve Solutions?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 3-Aminophenylboronic acid monohydrate.
How can I request a sample or quote for 3-Aminophenylboronic acid monohydrate?
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Please contact our sales team via the website or by phone to request a sample or a quotation for 3-Aminophenylboronic acid monohydrate.
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