O-[2-(3-Mercaptopropionylamino)ethyl]-O′-methylpolyethylene glycol

CAS 401916-61-8Polymer Science

O-[2-(3-Mercaptopropionylamino)ethyl]-O′-methylpolyethylene glycol (CAS: 401916-61-8) is a specialised monofunctional polyethylene glycol derivative. It features a terminal thiol group, enabling conjugation to various substrates, and a methyl-terminated polyethylene glycol chain which imparts water solubility and biocompatibility. This compound is primarily utilised in materials science and polymer chemistry for surface modification, bioconjugation, and the development of advanced functional materials.

IUPAC: ‘Mercaptopolyethylene glycol monomethyl ether’,PEG-thiol
Synonyms: ‘Mercaptopropionylamino)ethyl]-O′-methylpolyethylene glycolPEG-thiolMercaptopolyethylene glycol monomethyl ether

Email us

O-[2-(3-Mercaptopropionylamino)ethyl]-O′-methylpolyethylene glycol — chemical structure, CAS 401916-61-8; Materials Science, fine chemical supplied by Tech Serve Solutions

Materials ScienceMonofunctional PEGsPolymer SciencePolymersThiol More...

01 /Applications

Surface Modification

This thiol-terminated PEG derivative can be used to functionalise surfaces with polyethylene glycol chains. This is valuable for creating biocompatible coatings, reducing non-specific protein adsorption, and controlling surface properties in biomaterials and nanotechnology.

Bioconjugation

The terminal thiol group readily reacts with activated surfaces, such as maleimides or halides, allowing for the covalent attachment of the PEG chain to biomolecules like peptides, proteins, or antibodies. This process can improve the stability and pharmacokinetics of therapeutic agents.

Polymer Synthesis and Crosslinking

As a monofunctional PEG, it can be incorporated into polymer structures to control chain length and introduce specific end-group functionalities. It can also participate in crosslinking reactions, contributing to the formation of hydrogels and other polymeric networks.

Materials Science Research

Researchers in materials science utilise this compound for developing novel materials with tailored properties, including drug delivery systems, advanced coatings, and components for biosensors.

02 /Properties

Storage temperature	−20°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

401916-61-8

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is O-[2-(3-Mercaptopropionylamino)ethyl]-O′-methylpolyethylene glycol used for?

This compound is used in materials science and polymer chemistry for applications such as surface modification, bioconjugation, and the synthesis of functional polymers and hydrogels due to its terminal thiol group and PEG chain.

What is the CAS number and formula for O-[2-(3-Mercaptopropionylamino)ethyl]-O′-methylpolyethylene glycol?

The CAS number is 401916-61-8. The chemical formula is not provided in the data.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this chemical for research and development purposes. The specific grade and purity are not detailed in the provided data; it is not represented as USP, BP, or EP grade.

How should O-[2-(3-Mercaptopropionylamino)ethyl]-O′-methylpolyethylene glycol be handled?

Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The substance has a WGK Germany rating of 3, indicating it is hazardous to water.

How is this product packed, shipped, and exported?

This product is typically stored at -20°C. Tech Serve Solutions, established in 1998, is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents.

How can I request a sample or quote for this chemical?

Please contact Tech Serve Solutions directly through our official channels to request a sample or a quotation for O-[2-(3-Mercaptopropionylamino)ethyl]-O′-methylpolyethylene glycol.