Idazoxan hydrochloride
Idazoxan hydrochloride (CAS 79944-56-2), with the empirical formula C11H12N2O2 · HCl and a molecular weight of 240.69 g/mol, is a selective alpha-2 adrenergic receptor antagonist. It functions as a research tool in pharmacology, particularly within neuroscience, to investigate adrenergic neurotransmission and imidazoline binding sites. Its properties make it valuable for studying receptor interactions and cellular signalling pathways in research settings.
- IUPAC
- (±)-2-[1,4-Benzodioxan-2-yl]-2-imidazoline hydrochloride,RX 781094
- Synonyms
- (±)-2-[1,4-Benzodioxan-2-yl]-2-imidazoline hydrochloride,RX 781094

Neuroscience Research
Idazoxan hydrochloride is utilised in neuroscience to explore the roles of alpha-2 adrenergic receptors in neurotransmission. It serves as a valuable antagonist for investigating the modulation of noradrenergic pathways and their impact on behaviour and physiological functions.
Pharmacological Studies
This compound is employed in in-vitro and in-vivo pharmacological studies to understand receptor binding affinities and downstream signalling effects. Its selectivity allows for targeted investigation of alpha-2 adrenoceptor pharmacology and related cellular mechanisms.
Cell Biology Investigations
Researchers use Idazoxan hydrochloride to probe cellular responses mediated by adrenergic receptors. It aids in dissecting cell signaling cascades and understanding the functional consequences of receptor antagonism in various cell types.
| Molecular weight | 240.69 |
|---|---|
| Empirical formula | C11H12N2O2 · HCl |
| Solubility | H2O: soluble50 mg/mL |

Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
| Safety statements (S) | 7 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ADRA2A(150), ADRA2B(151), ADRA2C(152) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Idazoxan hydrochloride used for?
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Idazoxan hydrochloride is primarily used as a selective alpha-2 adrenergic receptor antagonist in pharmacological and neuroscience research to study neurotransmission and receptor function.
What is the CAS number and formula for Idazoxan hydrochloride?
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The CAS number for Idazoxan hydrochloride is 79944-56-2, and its empirical formula is C11H12N2O2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Idazoxan hydrochloride as a research chemical. The specific assay and purity are detailed on the product's Certificate of Analysis. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling precautions for Idazoxan hydrochloride?
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Idazoxan hydrochloride is classified as dangerous (Danger, H301). Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, faceshields, and gloves. Avoid ingestion and dust formation. Refer to the Safety Data Sheet for full details.
Is Idazoxan hydrochloride a controlled substance?
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The provided data does not indicate that Idazoxan hydrochloride is a controlled substance.
How is Idazoxan hydrochloride packed, shipped, and exported?
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Idazoxan hydrochloride is packed and shipped according to international regulations for hazardous materials (UN 2811, 6.1, PGIII). As a global supplier, Tech Serve Solutions facilitates its export to qualified research institutions worldwide.
How can I request a sample or quote for Idazoxan hydrochloride?
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To request a sample or a quotation for Idazoxan hydrochloride, please contact the Tech Serve Solutions sales department via our website or direct inquiry channels.
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