Hydrocortisone 21-hemisuccinate sodium salt
Hydrocortisone 21-hemisuccinate sodium salt (CAS: 125-04-2), with the formula C25H33NaO8 and a molecular weight of 484.51 g/mol, is a water-soluble derivative of hydrocortisone. This bioactive small molecule is primarily utilised in biological research for its properties as a corticosteroid. Available as a powder, it serves as a valuable reagent in cell biology and studies involving cell signaling pathways.
- IUPAC
- 11β,17α,21-Trihydroxy-4-pregnene-3,20-dione 21-hemisuccinate sodium salt,Cortisol 21-hemisuccinate sodium salt
- Synonyms
- 11β,17α,21-Trihydroxy-4-pregnene-3,20-dione 21-hemisuccinate sodium saltCortisol 21-hemisuccinate sodium salt

Cell Biology Research
Hydrocortisone 21-hemisuccinate sodium salt is employed in cell biology to investigate the effects of corticosteroids on cellular functions. It can be used in cell culture experiments to modulate cell behaviour and responses.
Hormonal Signaling Studies
As a derivative of hydrocortisone, this compound is useful for studying steroid hormone signaling pathways. Its applications include research into the mechanisms of action of glucocorticoids and their impact on gene expression.
Cytokine and Growth Factor Research
This substance may be used in studies examining the interplay between steroid hormones and cytokines or growth factors. It can help elucidate how hormonal balance influences cellular communication and inflammatory responses.
| Molecular weight | 484.51 |
|---|---|
| Empirical formula | C25H33NaO8 |
| Assay | ≥95% (TLC) |
| Form | powder |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Product Line | BioReagent |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Hydrocortisone 21-hemisuccinate sodium salt used for?
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Hydrocortisone 21-hemisuccinate sodium salt is used in biological research, particularly in cell biology and studies of cell signaling and hormone action, due to its corticosteroid properties.
What is the CAS number and formula for Hydrocortisone 21-hemisuccinate sodium salt?
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The CAS number is 125-04-2 and the empirical formula is C25H33NaO8.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Hydrocortisone 21-hemisuccinate sodium salt with an assay of ≥95% (TLC). This product is intended for research use and is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling recommendations for this product?
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Handle with appropriate personal protective equipment, including eyeshields, gloves, and a P1 or N95 respirator filter, to avoid contact and inhalation. The product is classified under WGK Germany 3, indicating it is hazardous to water.
How is Hydrocortisone 21-hemisuccinate sodium salt packed and shipped?
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This compound is typically stored at -20°C and supplied as a powder. TSS exports chemicals globally, ensuring appropriate packaging and documentation for international shipment.
How can I request a quote or sample?
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To request a quote or sample of Hydrocortisone 21-hemisuccinate sodium salt, please contact the TSS sales department through our website or by calling our customer service line.
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