Genistein
Genistein (CAS 446-72-0, C15H10O5, MW 270.24) is a naturally occurring isoflavone derived from soybeans. It is recognized for its biological activity, particularly as an inhibitor of various enzymes and a modulator of cellular processes. Genistein is extensively studied for its potential applications in cancer research and as a chemopreventive agent, owing to its impact on cell signaling pathways and angiogenesis.
- IUPAC
- 4′,5,7-Trihydroxyisoflavone,5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
- Synonyms
- 4',5,7-Trihydroxyisoflavone5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Cancer Research
Genistein is widely utilized in cancer research due to its ability to influence cell proliferation, apoptosis, and angiogenesis. It serves as a valuable tool for investigating novel therapeutic strategies and understanding cancer biology at a molecular level.
Angiogenesis Inhibition
This compound acts as an angiogenesis inhibitor, playing a role in research focused on conditions where the formation of new blood vessels is implicated. Its mechanism involves interfering with signaling pathways that promote vascular growth.
Enzyme Inhibition Studies
Genistein is employed as an enzyme inhibitor in biochemical and pharmacological studies. Its interactions with various kinases and other enzymes provide insights into cellular signaling cascades and potential drug targets.
Cell Biology Research
As a bioactive small molecule, Genistein is used to probe cellular functions and signaling pathways. It helps researchers investigate cell cycle regulation, signal transduction, and other fundamental cellular processes.
| Molecular weight | 270.24 |
|---|---|
| Empirical formula | C15H10O5 |
| Assay | ≥98% (HPLC) |
| Solubility | DMSO: solubleethanol: soluble |
| Storage temperature | −20°C |
| Biological source | from Glycine max (soybean) |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | Eyeshields, Faceshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Genistein used for?
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Genistein is used in scientific research, primarily in cancer research, angiogenesis inhibition studies, enzyme inhibition, and general cell biology investigations due to its bioactive properties.
What are the CAS number and chemical formula for Genistein?
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Genistein has the CAS number 446-72-0 and the chemical formula C15H10O5.
What grade and purity does Tech Serve Solutions supply for Genistein?
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Tech Serve Solutions supplies Genistein with a purity of ≥98% (HPLC). This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or pharmaceutical grade.
How should Genistein be handled and stored?
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Genistein is classified as harmful if swallowed (H302). Handle with appropriate personal protective equipment, including eyeshields, face shields, gloves, and a type N95 respirator filter. Store at -20°C.
How is Genistein packed and shipped?
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Genistein is typically packed in appropriate containers suitable for chemical transport and can be exported globally by Tech Serve Solutions.
How can I request a quote or sample for Genistein?
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To request a quote or sample for Genistein, please contact the Tech Serve Solutions sales team through our website or designated contact channels.
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