Galanthamine hydrobromide from Lycoris sp.
Galanthamine hydrobromide (CAS 1953-04-4, C17H21NO3·HBr, MW 368.27) is a potent acetylcholinesterase inhibitor isolated from plants of the Lycoris genus. This bioactive small molecule is a critical research chemical and a key reference standard in neuroscience and pharmacology. It functions by reversibly inhibiting acetylcholinesterase, thereby increasing acetylcholine levels in the brain. Its primary applications lie in biochemical research and as an analytical standard for related compounds.
- IUPAC
- Galantamine hydrobromide
Cholinesterase Inhibition Studies
Used as a selective and reversible inhibitor of acetylcholinesterase for in vitro and in vivo studies investigating cholinergic neurotransmission and its role in neurological processes.
Neuroscience Research
Essential reagent in neuroscience research for exploring the mechanisms of memory, cognition, and neurodegenerative diseases where acetylcholine plays a significant role.
Analytical Reference Standard
Serves as an analytical standard for the identification and quantification of galanthamine and related alkaloids in various matrices.
Biochemical Assays
Utilised in biochemical assays to study enzyme kinetics and interactions, particularly focusing on acetylcholinesterase activity and inhibition.
| Molecular weight | 368.27 |
|---|---|
| Empirical formula | C17H21NO3 · HBr |
| Assay | ≥94% (TLC) |
| Storage temperature | −20°C |
Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Galanthamine hydrobromide (CAS 1953-04-4) used for?
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Galanthamine hydrobromide is primarily used in biochemical research as an acetylcholinesterase inhibitor and in neuroscience studies investigating cholinergic pathways. It also functions as an analytical reference standard.
What is the CAS number and formula for Galanthamine hydrobromide?
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The CAS number is 1953-04-4, and the empirical formula is C17H21NO3·HBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Galanthamine hydrobromide with a purity of ≥94% (TLC). TSS does not represent this product as USP, BP, or EP grade.
What are the safety precautions for handling Galanthamine hydrobromide?
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Galanthamine hydrobromide is classified as acutely toxic (H301). Handle with extreme caution, using appropriate personal protective equipment including eyeshields, faceshields, gloves, and P2 respirator cartridges. Ensure adequate ventilation and follow emergency procedures (P301 + P310).
How is Galanthamine hydrobromide packed and shipped?
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This product is typically stored at -20°C. It is shipped as a hazardous material under UN 2811, Class 6.1, Packing Group III.
How can I request a sample or quote for Galanthamine hydrobromide?
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To request a sample or a quotation for Galanthamine hydrobromide, please contact our sales department via the website or by phone.
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