Fura-2 LeakRes (AM)

CAS 172890-84-5C55H63N5O29Biochemicals & Reagents

Fura-2 LeakRes (AM) (CAS: 172890-84-5), a crucial calcium indicator, possesses the molecular formula C55H63N5O29 and a molecular weight of 1258.10. This acetoxymethyl ester derivative of Fura-2 is engineered for enhanced resistance to leakage during cellular imaging. It is primarily utilised in ratiometric measurements and digital imaging microscopy for quantifying intracellular calcium levels with improved accuracy and reduced signal loss.

IUPAC: Fura PE 3-AM

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Fura-2 LeakRes (AM) (C55H63N5O29) — chemical structure, CAS 172890-84-5; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesBiochemicals and ReagentsCalcium IndicatorsCell BiologyChelators and Ion ProbesFluorescent ProbesLabelsParticles and Stains

01 /Applications

Ratiometric Calcium Imaging

Fura-2 LeakRes (AM) enables precise ratiometric measurements of intracellular calcium ion concentrations. Its design minimizes dye leakage, ensuring more stable and reliable data acquisition during long-term imaging studies.

Digital Imaging Microscopy

This indicator is highly suitable for high-resolution digital imaging microscopy. It allows for detailed visualisation and quantification of calcium dynamics within living cells and tissues.

Cellular Physiology Research

Used extensively in cell biology, Fura-2 LeakRes (AM) aids in understanding various cellular processes dependent on calcium signalling, such as muscle contraction, neurotransmitter release, and apoptosis.

02 /Properties

Molecular weight	1258.10
Empirical formula	C55H63N5O29
Assay	≥95% (TLC)
Grade	for fluorescence
Solubility	DMSO: soluble
Storage temperature	−20°C
Application	Fura 2 is one of the most widely used calcium indicators for ratiometric measurement and is highly suitable for digital imaging microscopy.

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

172890-84-5

MDL number

MFCD00285848

05 /Additional specifications

Fluorescence	λex 335 nm; λem 495 nm in 0.1 M Tris pH 8.0, esterase; 10 mM Ca2+

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Fura-2 LeakRes (AM) primarily used for?

Fura-2 LeakRes (AM) is used for ratiometric measurement of intracellular calcium levels, particularly in digital imaging microscopy, due to its resistance to leakage.

What is the CAS number and molecular formula for Fura-2 LeakRes (AM)?

The CAS number is 172890-84-5 and the molecular formula is C55H63N5O29.

What grade and purity does Tech Serve Solutions supply for Fura-2 LeakRes (AM)?

Tech Serve Solutions supplies Fura-2 LeakRes (AM) for fluorescence, with an assay of ≥95% (TLC). We do not represent this product as USP, BP, or EP grade.

How should Fura-2 LeakRes (AM) be handled and stored?

Handle Fura-2 LeakRes (AM) with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or P1 (EN143) respirator filter is recommended. Store at -20°C.

How is Fura-2 LeakRes (AM) packed, shipped, and exported?

Fura-2 LeakRes (AM) is carefully packed and exported by Tech Serve Solutions, adhering to international shipping regulations for chemical compounds. Specific packaging details are available upon request.