Filipin III from Streptomyces filipinensis
Filipin III from Streptomyces filipinensis (CAS: 480-49-9, C35H58O11) is a polyene macrolide antibiotic. This biochemical reagent is primarily utilized for its specific fluorescence properties in detecting and localizing unesterified cholesterol within biological samples. It also serves as a probe in double staining procedures for lipoproteins and can be immobilized on membranes for analytical applications, offering researchers a valuable tool for biochemical analysis.
Cholesterol Localization
Filipin III is widely employed to specifically localize and quantify unesterified cholesterol through the formation of a characteristic fluorescent complex, aiding in cell biology and lipid research.
Lipoprotein Detection
This compound has been utilized in a double staining technique as a probe for the identification of lipoproteins within polyacrylamide gels, contributing to protein analysis.
Membrane Immobilization
Filipin can be successfully immobilized onto nitrocellulose membranes, enabling its use in various assay formats for detecting specific biomolecules.
| Molecular weight | 654.83 |
|---|---|
| Empirical formula | C35H58O11 |
| Assay | ≥85% (HPLC) |
| Storage temperature | −20°C |
| Application | Filipin has been used in a double staining procedure as a probe for the detection of lipoproteins in polyacrylamide gel1 and immobilized on nitrocellulose membranes.2 It is also widely used to localize and quantitate unesterified cholesterol by virtue of a specific fluorescent complex.3 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Filipin III used for?
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Filipin III is used as a probe for detecting lipoproteins and localizing/quantifying unesterified cholesterol via a specific fluorescent complex. It can also be immobilized on membranes for analytical purposes.
What are the CAS number and formula for Filipin III?
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The CAS number for Filipin III is 480-49-9, and its molecular formula is C35H58O11.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Filipin III with an assay of ≥85% as determined by HPLC. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or pharmaceutical grade.
How should Filipin III be handled safely?
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Filipin III is a warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with a dust mask (type N95), eyeshields, and gloves. Ensure good ventilation. Avoid breathing dust.
Is Filipin III shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Filipin III, adhering to all relevant shipping regulations.
How can I request a quote or sample for Filipin III?
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To request a quote or sample for Filipin III, please contact our sales team through the website or by calling our customer service number.
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