Evans Blue
Evans Blue (CAS 314-13-6), with the molecular formula C34H24N6Na4O14S4, is a synthetic azo dye. It is known for its use as a vital stain in biological and medical research, particularly for evaluating vascular integrity and in histological staining. Its applications extend to assessing capillary permeability and as a diagnostic agent in certain veterinary procedures. This dye is supplied by Tech Serve Solutions for laboratory and research purposes.
- IUPAC
- Direct Blue 53
Vascular Permeability Assessment
Evans Blue is commonly used to assess the integrity of the blood-brain barrier and general vascular permeability in research models. It binds to albumin in the bloodstream, allowing visualization of leakage from blood vessels.
Histological Staining
As a dye, Evans Blue finds application in histology for staining specific tissues and cellular structures. It can be used in combination with other stains to enhance contrast and differentiate tissue components.
Diagnostic Tool in Veterinary Medicine
In certain veterinary contexts, Evans Blue has been employed as a diagnostic aid to evaluate physiological functions related to vascular systems. Its use is typically confined to research or specialized diagnostic procedures.
| Molecular weight | 960.81 |
|---|---|
| Empirical formula | C34H24N6Na4O14S4 |
| Form | powder |
| Composition | Dye content, ≥75% |
Hazard statements
- H301Toxic if swallowed
- H350May cause cancer
Precautionary statements
- P201Obtain special instructions before use
- P301IF SWALLOWED
- P308IF exposed or concerned
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 45-25 |
| Safety statements (S) | 53-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Colour Index Number | 23860 |
|---|---|
| Gene Information | human ... PTPN1(5770), PTPRF(5792) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Evans Blue used for?
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Evans Blue is primarily used as a vital stain in biological and medical research for assessing vascular permeability, evaluating the integrity of the blood-brain barrier, and in histological staining techniques.
What is the CAS number and chemical formula for Evans Blue?
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The CAS number for Evans Blue is 314-13-6, and its molecular formula is C34H24N6Na4O14S4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Evans Blue with a dye content of ≥75%. This product is intended for research and laboratory use, and TSS does not represent it as USP, BP, or EP grade.
What are the primary safety hazards associated with Evans Blue?
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Evans Blue is classified as toxic if swallowed (H301) and may cause cancer (H350). It requires careful handling; users must follow all safety precautions, including obtaining prior instructions before use (P201) and understanding the risks of exposure (P308 + P313).
How is Evans Blue packed and shipped?
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Evans Blue is shipped as a UN 2811, Hazard Class 6.1, Packing Group III substance, indicating it is a toxic solid. Standard laboratory packaging protocols are followed, adhering to all relevant shipping regulations for hazardous materials.
How can I request a sample or quote for Evans Blue?
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To request a sample or a quote for Evans Blue, please contact our sales department through the website or by phone. Our team will be pleased to assist you with your specific requirements.
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