Exemestane
Exemestane (CAS: 107868-30-4), with the molecular formula C20H24O2 and a molecular weight of 296.40 g/mol, is a white to off-white powder. This compound functions as an irreversible steroidal aromatase inactivator. It is primarily utilized in research settings for its role in cell biology, cell signaling, and as a hormone-related research chemical, particularly within studies involving steroid hormones and their pathways.
- IUPAC
- 6-Methyleneandrosta-1,4-diene-3,17-dione
- Synonyms
- 6-Methyleneandrosta-1,4-diene-3,17-dione

Aromatase Inhibition Research
Exemestane is used in vitro and in vivo research to study the effects of aromatase inhibition on various biological processes. Its irreversible mechanism makes it a valuable tool for investigating hormone-dependent pathways.
Cell Signaling Studies
As a steroid hormone modulator, Exemestane is employed in research to explore cellular signaling cascades influenced by estrogen levels. This aids in understanding complex cellular communication within research models.
Endocrinology Research Tool
Researchers utilise Exemestane to investigate the role of androgens and estrogens in physiological and pathological conditions. It serves as a critical reagent in endocrinology research.
| Molecular weight | 296.40 |
|---|---|
| Empirical formula | C20H24O2 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to off-white |
| Solubility | DMSO: ≥20 mg/mL |
| Optical activity | [α]/D +250 to +300°, c = 1 in methanol |
| Storage temperature | room temp |


Hazard statements
- H319Causes serious eye irritation
- H360May damage fertility or the unborn child
Precautionary statements
- P201Obtain special instructions before use
- P305IF IN EYES
- P308IF exposed or concerned
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | T,N |
| Risk statements (R) | 60-61-51 |
| Safety statements (S) | 53-22-36/37-57 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Exemestane used for?
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Exemestane is primarily used as a research chemical in areas such as cell biology, cell signaling, and endocrinology, particularly for studying aromatase inhibition and its effects on hormone pathways.
What are the CAS number and formula for Exemestane?
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The CAS number for Exemestane is 107868-30-4, and its molecular formula is C20H24O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Exemestane with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should Exemestane be handled and stored?
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Exemestane is classified as Danger with hazards including H319 (Causes serious eye irritation) and H360 (May damage fertility or the unborn child). Handle with appropriate personal protective equipment in a well-ventilated area, and store at room temperature.
Is Exemestane shipped internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Exemestane, serving researchers worldwide.
How can I request a sample or quote for Exemestane?
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To request a sample or a quote for Exemestane, please contact our sales team through the website or by phone.
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