Etomidate
Etomidate (CAS: 33125-97-2; Formula: C14H16N2O2; MW: 244.29 g/mol) is a non-barbiturate hypnotic agent. It functions as a positive allosteric modulator of GABA-A receptors, leading to central nervous system depression. Primarily utilised in anaesthesia for induction, its rapid onset and short duration make it valuable for short procedures and intubation. Available as a white powder, it is supplied by TSS with an assay of >98% HPLC.
- IUPAC
- Amidate,R16659

Anaesthetic Agent
Etomidate is employed as an intravenous anaesthetic for the induction of general anaesthesia. Its rapid onset of action and favourable haemodynamic profile make it suitable for patients with unstable cardiovascular conditions.
Sedation
In certain clinical settings, Etomidate can be used for short-term sedation. Its properties allow for controlled induction and recovery, facilitating brief medical interventions.
Neuroscience Research
As a modulator of GABA-A receptors, Etomidate serves as a valuable tool in neuroscience research to investigate inhibitory neurotransmission and neuronal excitability.
| Molecular weight | 244.29 |
|---|---|
| Empirical formula | C14H16N2O2 |
| Assay | >98% (HPLC) |
| Form | powder |
| Colour | white |
| Solubility | DMSO: >10 mg/mL |
| Storage temperature | 2-8°C |


Hazard statements
- H302Harmful if swallowed
- H400Very toxic to aquatic life
Precautionary statements
- P273Avoid release to the environment
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3077 9 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... GABRA1(2554) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Etomidate used for?
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Etomidate is primarily used for the induction of general anaesthesia and for short-term sedation. It acts as a positive allosteric modulator of GABA-A receptors.
What is the CAS number and formula for Etomidate?
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The CAS number for Etomidate is 33125-97-2, and its empirical formula is C14H16N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Etomidate with an assay of >98% by HPLC. It is not represented as USP, BP, EP, or pharmacopoeia grade.
How should Etomidate be handled safely?
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Handle Etomidate with appropriate personal protective equipment, including a dust mask (N95 US type), eyeshields, and gloves. It is classified as harmful if swallowed (H302) and very toxic to aquatic life (H400).
How is Etomidate packed, shipped, and exported?
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Etomidate is supplied as a white powder and stored at 2-8°C. It is shipped according to relevant regulations, including UN 3077 designation for environmentally hazardous substances. TSS is a global supplier and exporter.
How can I request a sample or quote for Etomidate?
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To request a sample or a quote for Etomidate, please contact our sales team through the TSS website or your dedicated account manager.
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