Ethynyltrimethylsilane
Ethynyltrimethylsilane (CAS: 1066-54-2) is a highly flammable organosilicon compound with the molecular formula (CH₃)₃SiC≡CH and a molecular weight of 98.22 g/mol. It is a versatile building block in organic synthesis, primarily utilised for introducing the trimethylsilylacetylene moiety into various molecular structures. Its reactivity makes it valuable in pharmaceuticals, agrochemicals, and materials science research.
- IUPAC
- Trimethylsilylacetylene
- Synonyms
- Trimethylsilylacetylene
Organic Synthesis Building Block
Ethynyltrimethylsilane serves as a key intermediate in the construction of complex organic molecules. Its terminal alkyne functionality, protected by the trimethylsilyl group, allows for controlled reactions such as Sonogashira couplings and cycloadditions.
Pharmaceutical Intermediate
This compound is employed in the synthesis of various pharmaceutical agents and drug candidates. It facilitates the introduction of specific structural elements required for biological activity.
Materials Science Research
Ethynyltrimethylsilane finds application in the development of novel materials, including polymers and functionalised surfaces, where its unique chemical properties can be leveraged.
| Molecular weight | 98.22 |
|---|---|
| Linear formula | (CH3)3SiC≡CH |
| Assay | ≥98.0% (GC) |
| Boiling point | 53 °C(lit.) |
| Density | 0.695 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.388(lit.) |
| Vapour pressure | 4.18 psi (20 °C) |
Hazard statements
- H225Highly flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | -34 °C / -29.2 °F |
| Transport (UN / ADR) | UN 1993BF 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-36/37/38 |
| Safety statements (S) | 16-26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethynyltrimethylsilane used for?
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Ethynyltrimethylsilane is primarily used as a versatile building block in organic synthesis, particularly for introducing the trimethylsilylacetylene group in the creation of pharmaceuticals, agrochemicals, and advanced materials.
What is the CAS number and chemical formula for Ethynyltrimethylsilane?
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The CAS number for Ethynyltrimethylsilane is 1066-54-2, and its linear chemical formula is (CH₃)₃SiC≡CH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethynyltrimethylsilane with an assay of ≥98.0% (GC). We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.
How should Ethynyltrimethylsilane be handled safely?
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Ethynyltrimethylsilane is highly flammable (Flash Point: -34 °C) and an irritant (H315, H319, H335). Handle with appropriate personal protective equipment, including gloves, goggles, and face shields, in a well-ventilated area, away from ignition sources.
How is Ethynyltrimethylsilane shipped and exported?
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Ethynyltrimethylsilane is shipped and exported under UN 1993, Flammable liquid, n.o.s. (Trimethylsilylacetylene), Class 3, Packing Group II. TSS adheres to all relevant international shipping regulations.
How can I request a sample or quote for Ethynyltrimethylsilane?
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To request a sample or obtain a quote for Ethynyltrimethylsilane, please contact our sales team through the website or by phone, providing your specific requirements.
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