Ethoxyacetylene solution
Ethoxyacetylene solution (CAS: 927-80-0) is a chemical compound supplied by TSS. Its formula is C2H5OC≡CH. This solution is approximately 40 wt.% in hexanes and is utilized in sophisticated organic synthesis. It serves as a key building block for creating complex molecules, including pyridines and unsaturated esters, through reactions like the Meyer-Schuster rearrangement. Stored under refrigeration, it is essential for advanced chemical research and development.

Pyridine Synthesis
Acts as a crucial reagent in the direct, three-component synthesis of pyridines when used with N-vinylamides and triflic anhydride.
Meyer-Schuster Rearrangement
Employed to prepare alpha,beta-unsaturated esters from ketones, leveraging the Meyer-Schuster rearrangement mechanism.
Organic Synthesis Building Block
Functions as a versatile terminal alkyne for constructing more complex organic structures in research and development.
| Molecular weight | 70.09 |
|---|---|
| Linear formula | C2H5OC≡CH |
| Density | 0.732 g/mL at 25 °C |
| Refractive index | n20/D 1.378 |
| Concentration | ~40 wt. % in hexanes |
| Storage temperature | 2-8°C |
| Application | Used with N-vinylamides and triflic anhydride in a direct, three-component synthesis of pyridines.1 Also used to prepare α,β-unsaturated esters from ketones via a Meyer-Schuster rearrangement.2 |



Hazard statements
- H304May be fatal if swallowed and enters airways
- H315Causes skin irritation
- H336May cause drowsiness or dizziness
- H361Suspected of damaging fertility or the unborn child
- H373May cause damage to organs through prolonged exposure
- H411Toxic to aquatic life with long-lasting effects
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P281Use personal protective equipment as required
- P301IF SWALLOWED
- P331Do NOT induce vomiting
| Transport (UN / ADR) | UN 1993BF 3 / PGII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 38-48/20-51/53-62-65-67 |
| Safety statements (S) | 36/37-61-62 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethoxyacetylene solution used for?
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Ethoxyacetylene solution is used in organic synthesis, notably for preparing pyridines and alpha,beta-unsaturated esters. It serves as a versatile building block in chemical synthesis.
What are the CAS number and formula for Ethoxyacetylene solution?
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The CAS number for Ethoxyacetylene solution is 927-80-0, and its linear formula is C2H5OC≡CH.
What is the grade or purity of this product?
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This product is supplied as a solution of approximately 40 wt.% ethoxyacetylene in hexanes. It is intended for chemical synthesis and research applications.
What are the main hazards associated with Ethoxyacetylene solution?
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Ethoxyacetylene solution presents hazards including aspiration toxicity (H304), skin irritation (H315), potential drowsiness or dizziness (H336), suspected of damaging fertility or the unborn child (H361), may cause damage to organs through prolonged exposure (H373), and is toxic to aquatic life with long-lasting effects (H411).
How is Ethoxyacetylene solution packed, shipped, and exported?
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The product is typically packed in accordance with UN 1993 BF 3 / PGII regulations for shipping. As a global supplier and exporter, TSS ensures compliant packaging and handling for international distribution.
How can I request a quote for Ethoxyacetylene solution?
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To request a quote, please contact our sales team directly through the TSS website or by calling our sales department. Please specify the quantity and any specific delivery requirements.
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