Endothelin 3 human, rat

CAS 117399-93-6C121H168N26O33S4Biochemicals & Reagents

Endothelin 3 (human, rat) (CAS: 117399-93-6) is a peptide agonist with a molecular weight of 2643.04 g/mol. This potent vasoconstrictor plays a crucial role in various physiological processes, including neural crest development and mammalian embryogenesis. It is primarily utilised in research settings to investigate cardiovascular regulation, neurodevelopment, and related biological pathways. Available as a white powder, this peptide is supplied by TSS for laboratory and research applications.

IUPAC: ET-3
Synonyms: ET-3Endothelin 3

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Endothelin 3 human, rat (C121H168N26O33S4) — chemical structure, CAS 117399-93-6; Life Science, fine chemical supplied by Tech Serve Solutions

AgonistsBiochemicals and ReagentsCell BiologyEndothelinsGPCR ModulatorsGPCR ProteinsModulators and AntibodiesPeptides and ProteinsPeptides for Cell Biology

01 /Applications

Neurodevelopmental Research

Endothelin 3 is investigated for its role in the development of the nervous system, particularly the neural crest, which gives rise to various cell types. Its influence on cell migration and differentiation makes it a valuable tool in understanding congenital disorders.

Cardiovascular Physiology Studies

As a potent vasoconstrictor, Endothelin 3 is used to study the mechanisms of blood pressure regulation and vascular tone. Researchers utilise this peptide to explore the endothelin receptor pathways involved in cardiovascular function.

Embryogenesis Research

This peptide is essential for studying mammalian embryogenesis, influencing critical developmental processes. Its involvement in cell proliferation and differentiation makes it a key subject in developmental biology research.

GPCR Signalling Investigations

Endothelin 3 acts as a ligand for endothelin receptors, which are G-protein coupled receptors (GPCRs). It is therefore employed in studies focusing on GPCR signalling pathways and their downstream effects in various cell types.

02 /Properties

Molecular weight	2643.04
Empirical formula	C121H168N26O33S4
Assay	≥97% (HPLC)
Form	powder
Colour	white
Storage temperature	−20°C
Composition	Peptide content, ~60%

03 /Identifiers & registry

CAS number

117399-93-6

MDL number

MFCD00076378

04 /Additional specifications

Gene Information	human ... EDN3(1908)rat ... Edn3(366270)

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Endothelin 3 (human, rat) used for?

Endothelin 3 (human, rat) is used in research for studying neurodevelopment, cardiovascular physiology, embryogenesis, and GPCR signalling pathways.

What is the CAS number and formula for Endothelin 3 (human, rat)?

The CAS number is 117399-93-6 and the empirical formula is C121H168N26O33S4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Endothelin 3 (human, rat) with a purity of ≥97% (HPLC). TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated.

How should Endothelin 3 (human, rat) be handled and stored?

Endothelin 3 (human, rat) has a WGK Germany rating of 3, indicating it is hazardous to water. It should be stored at -20°C. Please refer to the Safety Data Sheet for detailed handling instructions.

How is Endothelin 3 (human, rat) packed, shipped, and exported?

Endothelin 3 (human, rat) is carefully packed and prepared for shipment according to international regulations. Tech Serve Solutions is experienced in exporting fine chemicals globally.

How can I request a sample or a quote for Endothelin 3 (human, rat)?

To request a sample or obtain a quote, please contact our sales department via the website or by phone, providing the product name and CAS number (117399-93-6).