Endothelin 1
Endothelin 1 (CAS: 117399-94-7), with the molecular formula C109H159N25O32S5, is a potent vasoconstrictor and a key peptide involved in regulating blood pressure and vascular tone. It acts as a signalling molecule, playing critical roles in cardiovascular physiology and pathophysiology. Primarily used in biochemical research, Endothelin 1 serves as a valuable tool for studying cellular signalling pathways, particularly those related to the cardiovascular and nervous systems.
- IUPAC
- ET-1
Cardiovascular Research
Endothelin 1 is widely used in preclinical research to investigate the mechanisms of hypertension, endothelial dysfunction, and other cardiovascular diseases. Its potent vasoactive properties make it an essential tool for studying vascular tone regulation.
Cell Signalling Studies
As an endogenous peptide, Endothelin 1 is crucial for understanding G protein-coupled receptor (GPCR) signalling pathways. Researchers utilise it to study cellular responses and signal transduction cascades in various cell types.
Neuroscience Research
Endothelin 1 has demonstrated effects in the central nervous system, influencing neuronal excitability and vascular control. It is employed in studies exploring its role in neurological processes and disorders.
Endocrinology and Metabolism
This peptide is also implicated in endocrine functions and metabolic regulation. Its use in research helps elucidate its broader physiological and pathological impacts beyond the cardiovascular system.
| Molecular weight | 2491.90 |
|---|---|
| Empirical formula | C109H159N25O32S5 |
| Assay | ≥97.0% (HPLC) |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... EDN1(1906) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Endothelin 1 used for?
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Endothelin 1 (ET-1) is primarily used in biochemical and physiological research, particularly for studying cardiovascular regulation, cell signalling pathways, and its role in the nervous system. It acts as a potent vasoconstrictor and signalling peptide.
What is the CAS number and formula for Endothelin 1?
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The CAS number for Endothelin 1 is 117399-94-7, and its molecular formula is C109H159N25O32S5.
What grade and purity does Tech Serve Solutions supply for Endothelin 1?
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Tech Serve Solutions supplies Endothelin 1 with a purity of ≥97.0% as determined by HPLC. This product is intended for research purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should Endothelin 1 be handled and stored?
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Handle Endothelin 1 with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Store at -20°C.
How is Endothelin 1 packed, shipped, and exported by TSS?
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Tech Serve Solutions carefully packs, ships, and exports Endothelin 1 according to international regulations for fine chemicals. Specific packaging details can be provided upon request.
How can I request a sample or quote for Endothelin 1?
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To request a sample or a quotation for Endothelin 1, please contact the Tech Serve Solutions sales team through our website or by phone, referencing the product name and CAS number.
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